- ►nih.gov N Tiffin, E Adie, F Turner, HG Brunner, MA van … - Nucleic acids …, 2006 - Oxford Univ Press Genome-wide experimental methods to identify disease genes, such as linkage analysis and
association studies, generate increasingly large candidate gene sets for which comprehensive
empirical analysis is impractical. Computational methods employ data from a variety of ... Cited by 48 - Related articles - BL Direct - All 20 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains
differ in the response of their critical physiological functions, such as insulin sensitivity, ... Cited by 29 - Related articles - BL Direct - All 4 versions
G Cai, SA Cole, N Butte, C Bacino, V Diego, K Tan, HH … - Obesity, 2006 - nature.com Results: Significant heritabilities were seen for physical activity and dietary intake, ranging from
0.46 to 0.69, except for vigorous activity (h 2 = 0.18). Percentage time in sedentary activity mapped
to markers D18S1102-D18S64 on chromosome 18 [ logarithm of the odds (LOD) score = ... Cited by 24 - Related articles - All 4 versions
KE North, N Franceschini, IB Borecki, CC Gu, G Heiss, … - Diabetes, 2007 - Am Diabetes Assoc Recent studies have demonstrated the importance of sex effects on the underlying genetic architecture
of insulin-related traits. To explore sex-specific genetic effects on fasting insulin, we tested for
genotype-by-sex interaction and conducted linkage analysis of fasting insulin in ... Cited by 12 - Related articles - BL Direct - All 5 versions
S Sauerhöfer, G Yuan, GS Braun, M Deinzer, M … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—Fasting plasma glucose as well as A1C levels rose significantly earlier and remained
higher in transgenic animals throughout life. Body weights were reduced as a result of significant
glucosuria. In an opposite approach, nontransgenic db/db mice were supplemented with l- ... Cited by 12 - Related articles - BL Direct - All 3 versions
K Aston-Mourney, N Wong, M Kebede, S Zraika, L … - Diabetologia, 2007 - Springer Page 1. ARTICLE Increased nicotinamide nucleotide transhydrogenase levels predispose to
insulin hypersecretion in a mouse strain susceptible to diabetes K. Aston-Mourney & N. Wong
& M. Kebede & S. Zraika & L. Balmer & JM McMahon & BC Fam & J. Favaloro & ... Cited by 11 - Related articles - BL Direct - All 2 versions
ME Tejero, G Cai, HHH Göring, V Diego, SA Cole, … - International Journal of …, 2006 - nature.com The highest logarithm of odds (LOD) score (4.2) was found on chromosome
11q23.2–11q24.2, and a second significant signal (LOD score=3.0) was found on chromosome
8q12.1–8q21.3. In addition, a signal suggestive of linkage (LOD score=2.5) was found ... Cited by 7 - Related articles - BL Direct - All 15 versions
- ►shouxi.net S Puppala, R Arya, F Thameem, NH Arar, K Bhandari, … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—GFR (N = 453) was estimated using the recently recalculated
Cockcroft-Gault (GFR-CGc) and the simplified Modification of Diet in Renal Disease
(GFR-4VMDRD) formulae. Both estimates of GFR exhibited significant heritabilities, but ... Cited by 9 - Related articles - BL Direct - All 4 versions
MJ Moeller - Am Diabetes Assoc Page 1. L-carnosine, a substrate of carnosinase-1, influences glucose metabolism. Sibylle
Sauerhöfer, MD 1,2,5,6 , Gang Yuan, MD 1,2,6 , Gerald Stefan Braun, MD 2 , Martina Deinzer,
MD 3 , Michael Neumaier 3 , Professor of Medicine, Norbert Gretz, MD 4 , Jürgen ... Related articles
L Zhang, J Liu, HW Deng - Genetica - Springer Abstract Evaluating the patterns of linkage disequilib- rium (LD) is important for association mapping
study as well as for studying the genomic architecture of human genome (eg, haplotype block
structures). Commonly used bi-allelic pairwise measures for assessing LD between two ... Related articles - All 2 versions
