MC Thomas, JW Baynes, SR Thorpe, ME … - Current Drug …, 2005 - ingentaconnect.com Abstract: Prolonged hyperglycemia, dyslipidemia and oxidative stress in diabetes result in the
production and accumulation of AGEs. It is now clear that AGEs contribute to the development
and progression of cardiovascular disease in diabetes, as well as other complications. ... Cited by 42 - Related articles - All 2 versions
- ►diabetesjournals.org AG Huebschmann, JG Regensteiner, H Vlassara, … - Diabetes Care, 2006 - Am Diabetes Assoc The morbidity caused by diabetes has traditionally been classified into macro- and microvascular
complications. Although macrovascular complications have received greater attention, microvascular
complications are unique to diabetes, and hyperglycemia contributes to their ... Cited by 41 - Related articles - All 6 versions
- ►ebmonline.org GJ Brewer - Experimental Biology and Medicine, 2007 - SEBM In this review, we point out that natural selection does not act to lessen human diseases after
the reproductive and caregiving period and that normal levels of iron and copper that may be
healthy during the reproductive years appear to be contributing to diseases of aging and ... Cited by 36 - Related articles - All 5 versions
GJS Cooper, YK Chan, AM Dissanayake, FE Leahy, GF … - Diabetes, 2005 - Am Diabetes Assoc We recently showed that treatment with the Cu II -selective chelator, trientine, alleviates heart
failure in diabetic rats, improves left ventricular hypertrophy in humans with type 2 diabetes, and
increases urinary Cu excretion in both diabetic rats and humans compared with ... Cited by 28 - Related articles - All 9 versions
C Wihler, S Schäfer, K Schmid, EK Deemer, G Münch, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1645–1653 DOI 10.1007/s00125-005-1837-9
ARTICLE C. Wihler . S. Schäfer . K. Schmid . EK Deemer . G. Münch . M. Bleich . AE
Busch . T. Dingermann . V. Somoza . JW Baynes . J. Huber Renal ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►pasteur.ac.ir [PDF] GJ Brewer - Drug discovery today, 2005 - Elsevier Anticopper drugs that have been developed to treat Wilson's disease, a disease of copper
toxicity, include tetrathiomolybdate, zinc, penicillamine, and trientine. Lowering copper levels
by a modest amount in non-Wilson's patients with tetrathiomolybdate inhibits ... Cited by 22 - Related articles - All 6 versions
VM Monnier, DR Sell - Rejuvenation Research, 2006 - liebertonline.com The aging human extracellular matrix (ECM) and tissues rich in long-lived proteins undergo extensive
changes with age that include increased stiffening, loss of elasticity, insolubiliza- tion, and decreased
proteolytic digestibility. Most if not all these changes can be duplicated by the Maillard ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►physiology.org [PDF] S Glyn-Jones, S Song, MA Black, ARJ … - Physiological …, 2006 - Am Physiological Soc Page 1. Glyn-Jones et al. Transcriptomic analysis of DCM 1 Transcriptomic Analysis
of the Cardiac Left Ventricle in a Rodent Model of Diabetic Cardiomyopathy Molecular
Snapshot of a Severe Myocardial Disease Sarah Glyn ... Cited by 14 - Related articles - BL Direct - All 3 versions
Y Zheng, XK Li, Y Wang, L Cai - Hemoglobin, 2008 - informahealthcare.com Zinc (Zn), copper (Cu) and iron (Fe) are essential minerals that are required for a variety of biomolecules
to maintain the normal structure, function, and proliferation of cells. These metals can be toxic
in excessive amounts, especially in certain genetic disorders. The homeostasis of these ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org D Gong, J Lu, X Chen, SY Choong, S Zhang, YK Chan … - Molecular pharmacology, 2006 - ASPET Most patients with diabetes die from cardiac or arterial disease, for which there are limited therapeutic
options. Free Cu 2+ ions are strongly pro-oxidant, and chelatable-Cu II is increased in the diabetic
heart. We reported previously that treatment by Cu II -selective chelation with ... Cited by 10 - Related articles - All 6 versions
