L Bordone, MC Motta, F Picard, A Robinson, US … - PLoS …, 2006 - biology.plosjournals.org Sir2 and insulin/IGF-1 are the major pathways that impinge upon aging in lower organisms. In
Caenorhabditis elegans a possible genetic link between Sir2 and the insulin/IGF-1 pathway
has been reported. Here we investigate such a link in mammals. We show that Sirt1 ... Cited by 139 - Related articles - Cached - BL Direct - All 13 versions
- ►up.pt [PDF] M Lafontan - 2004 - Annual Reviews ▪ Abstract For a long time neural and endocrine messages were studied for their impact on adipocyte
metabolism and control of storage/release of fatty acids. In fact, bidirectional communication
exists between adipocytes and other tissues. Several molecules secreted from adipocytes ... Cited by 81 - Related articles - BL Direct - All 7 versions
- ►physiology.org JE Silva - Physiological reviews, 2006 - Am Physiological Soc Increased heat generation from biological processes is inherent to homeothermy. Homeothermic
species produce more heat from sustaining a more active metabolism as well as from reducing
fuel efficiency. This article reviews the mechanisms used by homeothermic species to ... Cited by 77 - Related articles - BL Direct - All 4 versions
P Trayhurn - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Obesity is a multidisciplinary area, the 'biology' of which encompasses: (1) the fundamental mechanisms
of energy balance and its regulation; (2) the biological basis for the development of obesity;
(3) adipose tissue function; (4) the biological description of the obese state; (5) the ... Cited by 66 - Related articles - All 6 versions
- ►physiology.org SR Bailey, S Mitra, S Flavahan, NA … - American Journal of …, 2005 - Am Physiological Soc Cold constricts cutaneous blood vessels by selectively increasing the activity of smooth muscle
2 -adrenoceptors ( 2 -ARs). In mouse tail arteries, 2 -AR constriction is mediated by 2A -ARs
at 37°C, whereas the cold-induced augmentation in 2 -AR activity is mediated entirely by ... Cited by 56 - Related articles - BL Direct - All 4 versions
RL House, JP Cassady, EJ Eisen, MK McIntosh, J Odle - obesity reviews, 2005 - ncsu.edu Blackwell Science, LtdOxford, UKOBRobesity reviews1467-78812005 The International Association
for the Study of Obesity. 63247258Review ArticleConjugated linoleic acid evokes de-lipidation
RL House et al. ... Address reprint requests to: Dr J Odle, Box 7621, North Carolina State ... Cited by 46 - Related articles - View as HTML - BL Direct - All 8 versions
- ►endojournals.org S Collins, W Cao, J Robidoux - Molecular Endocrinology, 2004 - Endocrine Soc The three ßAR (ß-adrenergic receptor) subtypes (ß 1 AR, ß 2 AR, and ß 3 AR) are members of
the large family of G protein-coupled receptors, each of which is coupled to G s and increases
in intracellular cAMP levels. In white adipose tissues, catecholamine activation of the ... Cited by 48 - Related articles - BL Direct - All 7 versions
DN Criddle, J Murphy, G Fistetto, S Barrow, AV Tepikin, … - Gastroenterology, 2006 - Elsevier Intracellular delivery of ester induced oscillatory increases of [Ca 2+ ] C and calcium-activated
currents, inhibited acutely by caffeine (20 mmol/L), but not atropine, indicating involvement of
inositol trisphosphate receptor channels. The stronger effect of extracellular ester or acid ... Cited by 43 - Related articles - All 17 versions
M Anello, R Lupi, D Spampinato, S Piro, M Masini, U … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Little information is available on the insulin release properties of pancreatic
islets iso- lated from type 2 diabetic subjects. Since mitochondria represent the site where important
metabolites that regulate insulin secretion are generated, we studied insulin release as ... Cited by 43 - Related articles - All 3 versions
AM Valverde, M Benito, M Lorenzo… - Acta Physiologica Scandinavica, 2005 - med.uio.no Abstract Type 2 diabetes mellitus is a complex metabolic disease that occurs when insulin secretion
can no longer compensate insulin resistance in peripheral tissues. At the molecular level, insulin
resistance correlates with impaired insulin signalling. This review provides new insights ... Cited by 41 - Related articles - View as HTML - All 4 versions