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Scholar Results 1 - 10 of about 97 citing Seufert: Leptin effects on pancreatic β-cell gene expression and function. (0.07 sec) 

The metabolic syndrome

- drclaudiaanrig.com [PDF] 
RH Eckel, SM Grundy, PZ Zimmet - The Lancet, 2005 - Elsevier
The metabolic syndrome is a common metabolic disorder that results from the
increasing prevalence of obesity. The disorder is defined in various ways, but
in the near future a new definition(s) will be applicable worldwide. The ...
Cited by 1560 - Related articles - All 41 versions

Intracellular signalling pathways activated by leptin


G Frühbeck - Biochemical Journal, 2006 - pubmedcentral.nih.gov
Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure
resembling that of members of the long-chain helical cytokine family. It is
mainly produced by adipocytes in proportion to fat size stores, and was ...
Cited by 203 - Related articles - BL Direct - All 8 versions

Disorders of glucose metabolism in sleep apnea


NM Punjabi, VY Polotsky - Journal of Applied Physiology, 2005 - Am Physiological Soc
Sleep is a complex behavioral state that occupies one-third of the human life
span. Although viewed as a passive condition, sleep is a highly active and
dynamic process. The sleep-related decrease in muscle tone is associated ...
Cited by 110 - Related articles - BL Direct - All 6 versions

Leptin and atherosclerosis


J Beltowski - Atherosclerosis, 2006 - Elsevier
Leptin, a 167-amino acid peptide hormone produced by white adipose tissue, is
primarily involved in the regulation of food intake and energy expenditure.
Leptin receptors are expressed in many tissues including the cardiovascular ...
Cited by 92 - Related articles - All 18 versions

Adipose tissue: a regulator of inflammation


CE Juge-Aubry, E Henrichot, CA Meier - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
Adipose tissue is a highly active organ. In addition to storing calories as
triglycerides, it also secretes a large variety of proteins, including
cytokines, chemokines and hormone-like factors, such as leptin, adiponectin ...
Cited by 91 - Related articles - All 4 versions

Adipokines: implications for female fertility and obesity

- reproduction-online.org
M Mitchell, DT Armstrong, RL Robker, RJ … - Reproduction, 2005 - Soc Reprod Fertility
Obesity is associated with a diverse set of metabolic disorders, and has
reproductive consequences that are complex and not well understood. The adipose
tissue-produced leptin has dominated the literature with regards to female ...
Cited by 64 - Related articles - BL Direct - All 9 versions

Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes

- endojournals.org
Y Toyoshima, O Gavrilova, S Yakar, W Jou, S … - Endocrinology, 2005 - Endocrine Soc
Leptin has metabolic effects on peripheral tissues including muscle, liver, and
pancreas, and it has been successfully used to treat lipodystrophic diabetes, a
leptin-deficient state. To study whether leptin therapy can be used for ...
Cited by 47 - Related articles - BL Direct - All 5 versions

The clinical applications of a systems approach


AC Ahn, M Tewari, CS Poon, RS Phillips - PLoS Med, 2006 - medicine.plosjournals.org
Funding: ACA's work on this manuscript was supported by a National Institutes of
Health Institutional National Research Service Award, grant T32-AT0051-03. RSP
is supported by a National Institutes of Health Mid-Career Investigator ...
Cited by 37 - Related articles - Cached - All 13 versions

The pancreatic β cell is a key site for mediating the effects of leptin on glucose homeostasis

- wisc.edu [PDF] 
SD Covey, RD Wideman, C McDonald, S … - Cell Metabolism, 2006 - Elsevier
The hormone leptin plays a crucial role in maintenance of body weight and
glucose homeostasis. This occurs through central and peripheral pathways,
including regulation of insulin secretion by pancreatic β cells. To study ...
Cited by 36 - Related articles - All 8 versions

Regulation of pancreatic {beta}-cell mass and proliferation by SOCS-3

- endocrinology-journals.org
K Lindberg, SG Ronn, D Tornehave, H Richter, … - Journal of molecular endocrinology, 2005 - Soc Endocrinology
Growth hormone and prolactin are important growth factors for pancreatic
ß-cells. The effects exerted by these hormones on proliferation and on insulin
synthesis and secretion in ß-cells are largely mediated through the Janus ...
Cited by 26 - Related articles - BL Direct - All 3 versions


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