D Eberle, B Hegarty, P Bossard, P Ferre, F … - Biochimie, 2004 - Elsevier Sterol regulatory element binding proteins (SREBPs) are a family of
transcription factors that regulate lipid homeostasis by controlling the
expression of a range of enzymes required for endogenous cholesterol, fatty ... Cited by 185 - Related articles - All 3 versions
- ►nih.gov BD Hegarty, A Bobard, I Hainault, P Ferré, P … - Proceedings of the National Academy of Sciences of …, 2005 - National Acad Sciences Sterol regulatory element-binding proteins (SREBPs) are transcription factors
central to the regulation of lipid metabolism. The SREBPs are synthesized as
precursor proteins that require proteolytic processing to become ... Cited by 79 - Related articles - All 10 versions
- ►aspetjournals.org SP Anderson, C Dunn, A Laughter, L Yoon, C … - Molecular pharmacology, 2004 - ASPET Lipid homeostasis is controlled in part by the nuclear receptors peroxisome
proliferator (PP)-activated receptor (PPAR ) and liver X receptor (LXR) through
regulation of genes involved in fatty acid and cholesterol metabolism. ... Cited by 49 - Related articles - BL Direct - All 5 versions
- ►jlr.org SL Sabol, HB Brewer Jr, S Santamarina-Fojo - The Journal of Lipid Research, 2005 - ASBMB The ABC transporter ABCG1 (ATP binding cassette transporter G1), expressed in
macrophages, liver, and other tissues, has been implicated in the efflux of
cholesterol to high density lipoprotein. The ABCG1 gene is ... Cited by 50 - Related articles - BL Direct - All 4 versions
W Insull Jr - South Med J, 2006 - pdfs.journals.lww.com Abstract: Bile acid sequestrants (BAS) continue to command a position in the
treatment of dyslipidemias 25 years after their intro- duction. Partial
diversion of the enterohepatic circulation using BAS depletes the ... Cited by 40 - Related articles - BL Direct - All 10 versions
P Ferre, F Foufelle - Horm Res, 2007 - content.karger.com Insulin has long-term effects on glucose and lipid metabolism through its
control on the expression of specific genes. In insulin sensitive tissues and
particularly in the liver, the transcription factor sterol regulatory ... Cited by 39 - Related articles - BL Direct - All 5 versions
EG Lund, LB Peterson, AD Adams, MHN Lam, … - Biochemical pharmacology, 2006 - Elsevier Liver X receptor (LXR) α and LXRβ are closely related nuclear receptors that
respond to elevated levels of intracellular cholesterol by enhancing
transcription of genes that control cholesterol efflux and fatty acid ... Cited by 39 - Related articles - All 5 versions
- ►diabetesjournals.org JC Henquin - Diabetes, 2004 - Am Diabetes Assoc Physiologically, insulin secretion is subject to a dual, hierarchal control by
triggering and amplifying pathways. By closing ATP-sensitive K + channels (K ATP
channels) in the plasma membrane, glucose and other metabolized nutrients ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org ET Kase, AJ Wensaas, V Aas, K Højlund, K … - Diabetes, 2005 - Am Diabetes Assoc Liver X receptors (LXRs) are important regulators of cholesterol and lipid
metabolism and are also involved in glucose metabolism. However, the functional
role of LXRs in human skeletal muscle is at present unknown. This study ... Cited by 37 - Related articles - All 6 versions
- ►shouxi.net M Albers, B Blume, T Schlueter, MB Wright, I … - Journal of Biological Chemistry, 2006 - ASBMB Partial, selective activation of nuclear receptors is a central issue in
molecular endocrinology but only partly understood. Using LXRs as an example, we
show here that purely agonistic ligands can be clearly and quantitatively ... Cited by 36 - Related articles - BL Direct - All 10 versions
