- ►asnjournals.org MD Breyer, E Bottinger, FC Brosius III, TM … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Mice provide an experimental model of unparalleled flexibility for studying
mammalian diseases. Inbred strains of mice exhibit substantial differences in
their susceptibility to the renal complications of diabetes. Much remains ... Cited by 104 - Related articles - All 6 versions
- ►ahajournals.org Y Hu, D Belke, J Suarez, E Swanson, R Clark … - Circulation research, 2005 - Am Heart Assoc To examine whether excessive protein O-GlcNAcylation plays a role in the
dysfunction of the diabetic heart, we delivered adenovirus expressing
O-GlcNAcase (Adv-GCA) into the myocardium of STZ-induced diabetic mice. Our ... Cited by 42 - Related articles - All 6 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►physiology.org SA Shore - Journal of applied physiology, 2007 - Am Physiological Soc Epidemiological data indicate that obesity is a risk factor for asthma. These
data are supported by observations in several murine models of obesity. Ob/ob,
db/db, and Cpe fat mice each exhibit innate airway hyperresponsiveness, a ... Cited by 23 - Related articles - BL Direct - All 8 versions
- ►endojournals.org EH Leiter, PC Reifsnyder, W Zhang, H Pan, Q … - Endocrinology, 2006 - Endocrine Soc Polygenic mouse models for obesity-induced type 2 diabetes (T2D) more accurately
reflect the most common manifestations of the human disease. Two inbred mouse
strains (NON/Lt and NZO/HlLt) separately contributed T2D susceptibility- ... Cited by 14 - Related articles - BL Direct - All 5 versions
WT Cefalu - ILAR JOURNAL, 2006 - dels.nas.edu The prevalence of diabetes throughout the world has in- creased dramatically
over the recent past, and the trend will continue for the foreseeable future.
One of the major con- cerns associated with diabetes relates to the ... Cited by 14 - Related articles - View as HTML - BL Direct - All 3 versions
- ►oxfordjournals.org K Togawa, M Moritani, H Yaguchi, M Itakura - Human Molecular Genetics, 2006 - Oxford Univ Press Most quantitative trait loci (QTL) studies have focused on detecting the genetic
effects of individual QTLs. This study thoroughly dissected the genetic
components of type 2 diabetic mice, including a search for epistatic ... Cited by 13 - Related articles - BL Direct - All 7 versions
- ►endojournals.org D Tsao, HK Thomsen, J Chou, J Stratton, M … - Endocrinology, 2008 - Endocrine Soc Mutations in the tyrosine kinase receptor trkB or in one of its natural ligands,
brain-derived neurotrophic factor (BDNF), lead to severe hyperphagia and obesity
in rodents and/or humans. Here, we show that peripheral administration of ... Cited by 11 - Related articles - BL Direct - All 3 versions
N Neubauer, RN Kulkarni - ILAR JOURNAL, 2006 - dels.nas.edu Type 2 diabetes is a polygenic disease that can lead to severe complications in
multiple tissues. Rodent models have been used widely for investigating the
pathophysiol- ogy underlying type 2 diabetes and for examining the po- ... Cited by 8 - Related articles - View as HTML - BL Direct - All 2 versions
