C Wolfrum, E Asilmaz, E Luca, JM Friedman, M … - Nature, 2004 - nature.com The regulation of fat and glucose metabolism in the liver is controlled
primarily by insulin and glucagon. Changes in the circulating concentrations of
these hormones signal fed or starvation states and elicit ... Cited by 127 - Related articles - All 6 versions
- ►diabetesjournals.org JC Henquin - Diabetes, 2004 - Am Diabetes Assoc Physiologically, insulin secretion is subject to a dual, hierarchal control by
triggering and amplifying pathways. By closing ATP-sensitive K + channels (K ATP
channels) in the plasma membrane, glucose and other metabolized nutrients ... Cited by 37 - Related articles - BL Direct - All 4 versions
BR Huber, ML Bulyk - BMC bioinformatics, 2006 - biomedcentral.com A key step in the regulation of gene expression is the sequence-specific binding
of transcription factors (TFs) to their DNA recognition sites. However,
elucidating TF binding site (TFBS) motifs in higher eukaryotes has been ... Cited by 23 - Related articles - Cached - All 10 versions
B Gross, B Staels - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier Patients with type-2 diabetes mellitus (T2DM) are considered to be at
particularly high risk for cardiovascular disease. Over the last decade, the
members of the peroxisome proliferator-activated receptor (PPAR) subfamily ... Cited by 19 - Related articles - All 15 versions
- ►bmj.com JR Porter, TG Barrett - British Medical Journal, 2005 - jmg.bmj.com Type 2 diabetes mellitus is caused by a combination of insulin resistance and ß
cell failure. The polygenic nature of type 2 diabetes has made it difficult to
study. Although many candidate genes for this condition have been ... Cited by 15 - Related articles - BL Direct - All 10 versions
MJ Park, MY Lee, JH Choi, HK Cho, YH Choi, … - FEBS journal, 2007 - interscience.wiley.com Adipocyte differentiation is an ordered multistep process requiring the
sequential activation of several groups of adipogenic transcription factors,
including CCAAT/enhancer-binding protein-α and peroxisome proliferator- ... Cited by 4 - Related articles - BL Direct - All 5 versions
- ►physiology.org I Walter, F Seebacher - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc In endotherms, plasticity of internal heat production in response to
environmental variability is an important component of thermoregulation. During
embryogenesis endotherms cannot regulate their body temperature ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►cell.com H Wang, CB Wollheim - Trends in Molecular Medicine, 2005 - Elsevier Foxa2 (Hnf3β) is a winged-helix/forkhead transcription factor that regulates
gene expression in the liver, pancreatic islets and adipocytes. It is required
for the maintenance of glucose and lipid homeostasis. ... Cited by 3 - Related articles - All 7 versions
MA de Barros Reis, VC Arantes, DA Cunha, … - The Journal of nutritional biochemistry, 2008 - Elsevier Intrauterine growth restriction is associated with chronically elevated levels
of serum fatty acids and reduced glucose-stimulated insulin secretion. Lipid
metabolism in pancreatic β cells is critical for the regulation of insulin ... Cited by 2 - Related articles - All 8 versions
