H Kolb, T Mandrup-Poulsen - Diabetologia, 2005 - Springer Abstract Subclinical, low-grade systemic inflammation has been observed in patients with type 2
diabetes and in those at increased risk of the disease. This may be more than an epiphenomenon.
Alleles of genes encoding immune/ ... Cited by 118 - Related articles - BL Direct - All 5 versions
- ►jbc.org FG De Felice, PT Velasco, MP Lambert, K Viola, SJ … - Journal of Biological …, 2007 - ASBMB Oxidative stress is a major aspect of Alzheimer disease (AD) pathology. We have investigated the
relationship between oxidative stress and neuronal binding of A oligomers (also known as ADDLs).
ADDLs are known to accumulate in ... Cited by 91 - Related articles - All 5 versions
- ►medvetande.dk [PDF] B Van Houten, V Woshner, JH Santos - DNA repair, 2006 - Elsevier Mitochondria are at the crossroads of several crucial cellular activities including: adenosine
triphosphate (ATP) generation via oxidative phosphorylation; the biosynthesis of heme, pyrimidines
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JA Hawley - Diabetes/Metabolism Reviews - interscience.wiley.com During the past half-century, there has been a dramatic increase in the incidence of obesity,
insulin resistance and type 2 diabetes. A hallmark feature of these conditions is impaired glucose
tolerance (IGT). Cross-sectional ... Cited by 63 - Related articles - BL Direct - All 4 versions
L Moldovan, NI Moldovan - Histochemistry and cell biology, 2004 - Springer Abstract The presence and supposed roles of reactive oxygen species (ROS) were reported in
literature in a myriad of instances. However, the breadth and depth of their involvement in cellular
physiology and pathology, as well ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org MN Sack - Cardiovascular research, 2006 - cardiovascres.oxfordjournals.org Modest depolarization of the mitochondrial inner membrane potential is known to attenuate
mitochondrial reactive oxygen species generation. Transient pharmacologic uncoupling of
mitochondrial oxidative ... Cited by 37 - Related articles - All 7 versions
- ►unige.ch [PDF] P Maechler, S Carobbio, B Rubi - International Journal of Biochemistry and Cell …, 2006 - Elsevier Pancreatic beta-cells are unique neuroendocrine cells displaying the peculiar feature of responding
to nutrients, principally glucose, as primary stimulus. This requires translation of a metabolic
substrate into intracellular ... Cited by 29 - Related articles - All 7 versions
- ►endocrinology-journals.org R Mastrocola, F Restivo, I Vercellinatto, O … - Journal of …, 2005 - Soc Endocrinology Diabetic encephalopathy, characterized by impaired cognitive functions and neurochemical and
structural abnormalities, may involve direct neuronal damage caused by intracellular glucose. The
study assesses the direct effect of ... Cited by 29 - Related articles - BL Direct - All 3 versions
JMI Malik, Z Shevtsova, M Bähr, S Kügler - Molecular Therapy, 2005 - Elsevier The inherently low regenerative capacity of the CNS demands effective strategies to inhibit
neurodegeneration in acute lesions but also in slowly progressive neurological disorders. Therefore,
therapeutic targets that can ... Cited by 26 - Related articles - All 6 versions
- ►cardiovascres.org SM Davidson, MR Duchen - Cardiovascular research, 2006 - cardiovascres.org Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac mitochondria
in particular remain controversial, it is now clear that both endogenous and exogenous sources of NO
exert important modulatory effects ... Cited by 26 - Related articles - All 6 versions
