- ►shouxi.net AP Babenko, M Polak, H Cave, K Busiah, P … - The New England journal of medicine, 2006 - nejm.highwire.org Background The ATP-sensitive potassium (K ATP ) channel, composed of the
beta-cell proteins sulfonylurea receptor (SUR1) and inward-rectifying potassium
channel subunit Kir6.2, is a key regulator of insulin release. It is ... Cited by 155 - Related articles - BL Direct - All 12 versions
CG Nichols - Nature, 2006 - nature.com Even in the absence of ATP, the single-channel kinetics of K ATP are complex,
but certain key features are clearly discernible and can be modelled by assuming
a single 'fast' gate and ligand-operated 'slow' gates within each subunit ... Cited by 135 - Related articles - BL Direct - All 8 versions
- ►physiology.org B Sarkadi, L Homolya, G Szakacs, A Varadi - Physiological reviews, 2006 - Am Physiological Soc In this review we give an overview of the physiological functions of a group of
ATP binding cassette (ABC) transporter proteins, which were discovered, and
still referred to, as multidrug resistance (MDR) transporters. Although ... Cited by 115 - Related articles - BL Direct - All 8 versions
- ►oxfordjournals.org P Proks, AL Arnold, J Bruining, C Girard, SE … - Human molecular genetics, 2006 - Oxford Univ Press Neonatal diabetes is a genetically heterogeneous disorder with nine different
genetic aetiologies reported to date. Heterozygous activating mutations in the
KCNJ11 gene encoding Kir6.2, the pore-forming subunit of the ATP-sensitive ... Cited by 76 - Related articles - BL Direct - All 9 versions
B Liss, O Haeckel, J Wildmann, T Miki, S … - Nature neuroscience, 2005 - uni-ulm.de The selective degeneration of dopaminergic (DA) midbrain neurons in the
substantia nigra (SN) is a hallmark of Parkinson disease. DA neurons in the
neighboring ventral tegmental area (VTA) are significantly less affected. ... Cited by 64 - Related articles - BL Direct - All 11 versions
- ►rug.nl [PDF] E Biemans-Oldehinkel, MK Doeven, B … - FEBS letters, 2006 - Elsevier We present an overview of the architecture of ATP-binding cassette (ABC)
transporters and dissect the systems in core and accessory domains. The ABC
transporter core is formed by the transmembrane domains (TMDs) and the ... Cited by 59 - Related articles - All 6 versions
MV Mikhailov, JD Campbell, H de Wet, K … - The EMBO Journal, 2005 - pubmedcentral.nih.gov ATP-sensitive potassium (K ATP ) channels conduct potassium ions across cell
membranes and thereby couple cellular energy metabolism to membrane electrical
activity. Here, we report the heterologous expression and purification of a ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►nih.gov BO'Rourke, 2007 - Annual Reviews Abstract In work spanning more than a century, mitochondria have been recognized
for their multifunctional roles in metabolism, energy transduction, ion
transport, inheritance, signaling, and cell death. Foremost among these ... Cited by 37 - Related articles - BL Direct - All 8 versions
F Wehner - Contributions to nephrology, 2006 - content.karger.com Abstract Considering the enormous turnover rates of ion channels when compared
to carriers it is quite obvious that channel-mediated ion transport may serve as
a rapid and efficient mechanism of cell volume regulation. Whenever studied ... Cited by 36 - Related articles - BL Direct - All 6 versions
- ►pubget.com [PDF] J Bryan, A Muñoz, X Zhang, M Düfer, G Drews … - Pflügers Archiv European Journal of Physiology, 2007 - Springer Abstract The sulfonylurea receptors (SURs) ABCC8/ SUR1 and ABCC9/SUR2 are
members of the C-branch of the transport adenosine triphosphatase superfamily.
Unlike their brethren, the SURs have no identified transport function; ... Cited by 31 - Related articles - BL Direct - All 6 versions
