- ►aspetjournals.org K Katsuno, Y Fujimori, Y Takemura, M Hiratochi, F … - Journal of Pharmacology …, 2007 - ASPET The low-affinity sodium glucose cotransporter (SGLT2), which is expressed specifically in the
kidney, plays a major role in renal glucose reabsorption in the proximal tubule. We have discovered
sergliflozin, a prodrug of a novel selective SGLT2 inhibitor, based on benzylphenol ... Cited by 31 - Related articles - All 5 versions
MM Ansar, M Ansari - Nitric Oxide, 2006 - Elsevier Glibenclamide as a second-generation compound of sulfonylurea has widely been used in the
treatment of type 2 diabetes patients. It has been shown that it induces apoptosis in β cells, which
is partially mediated by Ca 2+ influx. Here, we investigated the role of nitric oxide (NO) ... Cited by 8 - Related articles - All 3 versions
V Rambiritch, P Naidoo, N Butkow - Southern Medical Journal, 2007 - journals.lww.com Abstract: type 2 diabetes mellitus is currently a global health prob- lem. Although the armamentarium
of oral hypoglycemic agents is continuously expanding, sulfonylureas (SUs) are still extensively
used for the management of type 2 diabetes mellitus. However, despite decades of use, ... Cited by 2 - Related articles - BL Direct - All 3 versions
V Rambiritch, P Naidoo - Drugs, 2005 - pt.wkhealth.com Gliclazide MR is approximately three times more costly when compared with generic gliclazide
CR (manufacturer's price list). However, for patients requiring >160 mg/day of the gliclazide CR
preparation, and who are poorly compliant on twice-daily regimens as compared with ... Cited by 1 - Related articles - BL Direct - All 3 versions
P Naidoo, R Virendra, M Layla - Current Therapeutic Research, 2006 - Elsevier Methods: This prospective, open-label, case-controlled, dose-escalation study was conducted
at the Addington Hospital Diabetes Clinic, eThekwini/Durban, KwaZulu-Natal, South Africa. Male
and female patients aged ≥18 years with type 2 diabetes mellitus (DM) and postprandial ... Cited by 1 - Related articles - All 3 versions