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Scholar Results 1 - 10 of about 71 citing Winzell: The High-Fat Diet–Fed Mouse. (0.08 sec) 

Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin …

- uio.no [PDF] 
K Ohtsubo, S Takamatsu, MT Minowa, A … - Cell, 2005 - Elsevier
Pancreatic β cell-surface expression of glucose transporter 2 (Glut-2) is
essential for glucose-stimulated insulin secretion, thereby controlling blood
glucose homeostasis in response to dietary intake. We show that the murine ...
Cited by 69 - Related articles - All 18 versions

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research


QM Anstee, RD Goldin - International journal of experimental pathology, 2006 - interscience.wiley.com
Non-alcoholic fatty liver disease (NAFLD) represents a histological spectrum of
liver disease associated with obesity, diabetes and insulin resistance that
extends from isolated steatosis to steatohepatitis and cirrhosis. As well ...
Cited by 68 - Related articles - BL Direct - All 4 versions

Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the …

- cell.com
M Monetti, MC Levin, MJ Watt, MP Sajan, S … - Cell metabolism, 2007 - Elsevier
Hepatic steatosis, the accumulation of lipids in the liver, is widely believed
to result in insulin resistance. To test the causal relationship between hepatic
steatosis and insulin resistance, we generated mice that overexpress ...
Cited by 57 - Related articles - All 8 versions

Dipeptidyl peptidase-4 inhibitors

- diabetesjournals.org
B Ahrén - Diabetes Care, 2007 - Am Diabetes Assoc
The enzyme dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of
glucagon-like peptide-1 (GLP-1). Since GLP-1–based therapy is a promising
novel treatment of type 2 diabetes, the strategy to inhibit the enzyme has ...
Cited by 51 - Related articles - BL Direct - All 11 versions

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation


K Fukui, Q Yang, Y Cao, N Takahashi, H … - Cell Metabolism, 2005 - Elsevier
Defective glucose-stimulated insulin secretion is the main cause of
hyperglycemia in type 2 diabetes mellitus. Mutations in HNF-1α cause a
monogenic form of type 2 diabetes, maturity-onset diabetes of the young ...
Cited by 50 - Related articles - All 10 versions

Dual action of adiponectin on insulin secretion in insulin-resistant mice


MS Winzell, R Nogueiras, C Dieguez, B Ahrén - Biochemical and Biophysical Research …, 2004 - Elsevier
Adiponectin is secreted by adipocytes and has been implicated as a mediator of
insulin sensitivity. In this study, the acute effects of adiponectin on islets
isolated from normal or diet-induced insulin resistant mice were examined. ...
Cited by 40 - Related articles - All 4 versions

Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes: preclinical biology …

- diabetesjournals.org
DJ Drucker - Diabetes care, 2007 - Am Diabetes Assoc
Dipeptidyl peptidase (DPP)-4 is a complex enzyme that exists as a
membrane-anchored cell surface peptidase that transmits intracellular signals
via a short intracellular tail and as a second smaller soluble form present ...
Cited by 42 - Related articles - BL Direct - All 11 versions

Maternal high-fat diet consumption results in fetal malprogramming predisposing to the …

- physiology.org
M Srinivasan, SD Katewa, A Palaniyappan, … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Chronic consumption of a high-fat (HF) diet by female rats in their postweaning
period resulted in significant increases in body weight and plasma levels of
insulin, glucose, and triglycerides during pregnancy compared with female ...
Cited by 27 - Related articles - BL Direct - All 6 versions

[PDF] Animal model in type 2 diabetes research: An overview


K Srinivasan, P Ramarao - Indian Journal of Medical Research, 2007 - icmr.nic.in
Type 2 diabetes is a complex and heterogeneous disorder presently affecting more
than 100 million people worldwide and causing serious socio-economic problems.
Appropriate experimental models are essential tools for understanding the ...
Cited by 25 - Related articles - View as HTML - BL Direct - All 3 versions

[PDF] Dual role of proapoptotic BAD in insulin secretion and beta cell survival


NN Danial, LD Walensky, CY Zhang, CS Choi, … - Nature - unthsc.edu
The proapoptotic BCL-2 family member BAD resides in a glucokinase-containing
complex that regulates glucose-driven mitochondrial respiration. Here, we
present genetic evidence of a physiologic role for BAD in ...
Cited by 30 - Related articles - View as HTML - BL Direct - All 7 versions


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