- ►uio.no [PDF] K Ohtsubo, S Takamatsu, MT Minowa, A … - Cell, 2005 - Elsevier Pancreatic β cell-surface expression of glucose transporter 2 (Glut-2) is
essential for glucose-stimulated insulin secretion, thereby controlling blood
glucose homeostasis in response to dietary intake. We show that the murine ... Cited by 69 - Related articles - All 18 versions
QM Anstee, RD Goldin - International journal of experimental pathology, 2006 - interscience.wiley.com Non-alcoholic fatty liver disease (NAFLD) represents a histological spectrum of
liver disease associated with obesity, diabetes and insulin resistance that
extends from isolated steatosis to steatohepatitis and cirrhosis. As well ... Cited by 68 - Related articles - BL Direct - All 4 versions
- ►cell.com M Monetti, MC Levin, MJ Watt, MP Sajan, S … - Cell metabolism, 2007 - Elsevier Hepatic steatosis, the accumulation of lipids in the liver, is widely believed
to result in insulin resistance. To test the causal relationship between hepatic
steatosis and insulin resistance, we generated mice that overexpress ... Cited by 57 - Related articles - All 8 versions
- ►diabetesjournals.org B Ahrén - Diabetes Care, 2007 - Am Diabetes Assoc The enzyme dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of
glucagon-like peptide-1 (GLP-1). Since GLP-1–based therapy is a promising
novel treatment of type 2 diabetes, the strategy to inhibit the enzyme has ... Cited by 51 - Related articles - BL Direct - All 11 versions
K Fukui, Q Yang, Y Cao, N Takahashi, H … - Cell Metabolism, 2005 - Elsevier Defective glucose-stimulated insulin secretion is the main cause of
hyperglycemia in type 2 diabetes mellitus. Mutations in HNF-1α cause a
monogenic form of type 2 diabetes, maturity-onset diabetes of the young ... Cited by 50 - Related articles - All 10 versions
MS Winzell, R Nogueiras, C Dieguez, B Ahrén - Biochemical and Biophysical Research …, 2004 - Elsevier Adiponectin is secreted by adipocytes and has been implicated as a mediator of
insulin sensitivity. In this study, the acute effects of adiponectin on islets
isolated from normal or diet-induced insulin resistant mice were examined. ... Cited by 40 - Related articles - All 4 versions
- ►diabetesjournals.org DJ Drucker - Diabetes care, 2007 - Am Diabetes Assoc Dipeptidyl peptidase (DPP)-4 is a complex enzyme that exists as a
membrane-anchored cell surface peptidase that transmits intracellular signals
via a short intracellular tail and as a second smaller soluble form present ... Cited by 42 - Related articles - BL Direct - All 11 versions
- ►physiology.org M Srinivasan, SD Katewa, A Palaniyappan, … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Chronic consumption of a high-fat (HF) diet by female rats in their postweaning
period resulted in significant increases in body weight and plasma levels of
insulin, glucose, and triglycerides during pregnancy compared with female ... Cited by 27 - Related articles - BL Direct - All 6 versions
K Srinivasan, P Ramarao - Indian Journal of Medical Research, 2007 - icmr.nic.in Type 2 diabetes is a complex and heterogeneous disorder presently affecting more
than 100 million people worldwide and causing serious socio-economic problems.
Appropriate experimental models are essential tools for understanding the ... Cited by 25 - Related articles - View as HTML - BL Direct - All 3 versions
NN Danial, LD Walensky, CY Zhang, CS Choi, … - Nature - unthsc.edu The proapoptotic BCL-2 family member BAD resides in a glucokinase-containing
complex that regulates glucose-driven mitochondrial respiration. Here, we
present genetic evidence of a physiologic role for BAD in ... Cited by 30 - Related articles - View as HTML - BL Direct - All 7 versions