- ►endojournals.org BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc There is a progressive deterioration in ß-cell function and mass in type 2
diabetics. It was found that islet function was about 50% of normal at the time
of diagnosis, and a reduction in ß-cell mass of about 60% was shown at ... Cited by 100 - Related articles - BL Direct - All 7 versions
- ►nih.gov DJ Drucker - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The gastrointestinal tract has a crucial role in the control of energy
homeostasis through its role in the digestion, absorption, and assimilation of
ingested nutrients. Furthermore, signals from the gastrointestinal tract ... Cited by 82 - Related articles - BL Direct - All 11 versions
- ►glucagon.com [PDF] - Free from Publisher MC Riddle, DJ Drucker - Diabetes Care, 2006 - Am Diabetes Assoc Current therapies for type 2 diabetes are frequently associated with inadequate
control of postprandial hyperglycemia, weight gain, and, in the case of oral
agents, loss of efficacy over time. A better understanding of physiological ... Cited by 71 - Related articles - BL Direct - All 10 versions
N Irwin, PL McClean, FPM O'Harte, VA Gault, P … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP)
receptor action is reported to protect against obesity and associated metabolic
abnormalities. The aim of this study was to use prediabetic ob/ob mice to ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►qub.ac.uk [PDF] BD Green, PR Flatt - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are physiological gut peptides with
insulin-releasing and extrapancreatic glucoregulatory actions. Incretin ... Cited by 29 - Related articles - All 17 versions
JJ Meier, B Gallwitz, M Askenas, K Vollmer, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1872–1881 DOI 10.1007/s00125-005-1863-7 ARTICLE
JJ Meier . B. Gallwitz . M. Askenas . K. Vollmer . CF Deacon . JJ Holst . ... Cited by 25 - Related articles - BL Direct - All 3 versions
- ►aspetjournals.org N Irwin, BD Green, MH Mooney, B Greer, P … - Journal of Pharmacology and Experimental …, 2005 - ASPET Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone
with a potentially therapeutic role in type 2 diabetes. Rapid degradation by
dipeptidylpeptidase IV has prompted the development of enzyme-resistant N- ... Cited by 22 - Related articles - BL Direct - All 7 versions
BA Whitson, DB Leslie, TA Kellogg, MA … - Journal of Surgical Research, 2007 - Elsevier Mean patient age was 42 ± 11 years, and the mean preoperative body mass index
was 50 ± 6 kg/m 2 . At 6 months mean BMI fell to 33 ± 5 kg/m 2 (P < 0.0001),
and there were no differences between diabetics and nondiabetics with ... Cited by 20 - Related articles - All 16 versions
JJ Meier, MA Nauck - Current Diabetes Reports, 2006 - Springer The incretin hormones gastric inhibitory polypeptide (GIP) and glucagon-like
peptide 1 (GLP-1) are released in response to nutrient ingestion and potentiate
glucose- stimulated insulin secretion from pancreatic β cells. The ... Cited by 19 - Related articles - BL Direct - All 2 versions
- ►diabetica.co.uk [PDF] N Irwin, VA Gault, BD Green, B Greer, P … - Biological chemistry, 2005 - reference-global.com Fatty acid derivatisation was used to develop two novel, long-acting,
N-terminally modified, glucose-dependent insulinotropic polypeptide (GIP)
analogues, N-Ac- GIP(LysPAL16) and N-AcGIP(LysPAL37). In contrast to GIP, ... Cited by 17 - Related articles - BL Direct - All 10 versions
