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Scholar Results 1 - 10 of about 16 citing Shibasaki: Integration of ATP, cAMP, and Ca2+ signals in insulin granule exocytosis. (0.20 sec) 

PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

- physiology.org
S Seino, T Shibasaki - Physiological reviews, 2005 - Am Physiological Soc
Stimulus-secretion coupling is an essential process in secretory cells in which
regulated exocytosis occurs, including neuronal, neuroendocrine, endocrine, and
exocrine cells. While an increase in intracellular Ca 2+ concentration ([Ca ...
Cited by 145 - Related articles - BL Direct - All 4 versions

Cell physiology of cAMP sensor Epac

- nih.gov
GG Holz, G Kang, M Harbeck, MW Roe, OG … - The Journal of Physiology, 2006 - Physiological Soc
Epac is an acronym for the exchange proteins activated directly by cyclic AMP, a
family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs) that
mediate protein kinase A (PKA)-independent signal transduction properties ...
Cited by 64 - Related articles - BL Direct - All 32 versions

cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human …

- physoc.org
G Kang, OG Chepurny, B Malester, MJ … - The Journal of Physiology, 2006 - Physiological Soc
The Epac family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs,
also known as Epac1 and Epac2) mediate stimulatory actions of the second
messenger cAMP on insulin secretion from pancreatic β cells. Because Epac2 ...
Cited by 38 - Related articles - BL Direct - All 19 versions

Epac-selective cAMP analogs: New tools with which to evaluate the signal transduction …

- nih.gov
GG Holz, OG Chepurny, F Schwede - Cellular signalling, 2008 - Elsevier
The identification of 2′-O-methyl substituted adenosine-3′,5′-cyclic
monophosphate (cAMP) analogs that activate the Epac family of cAMP-regulated
guanine nucleotide exchange factors (cAMP-GEFs, also known as Epac1 and ...
Cited by 30 - Related articles - All 4 versions

Overexpression of SUR2A generates a cardiac phenotype resistant to ischemia

- fasebj.org
Q Du, S Jovanovic, A Clelland, A Sukhodub, G … - The FASEB Journal, 2006 - FASEB
ATP-sensitive K + (K ATP ) channels are present in the sarcolemma of cardiac
myocytes where they link membrane excitability with the cellular bioenergetic
state. These channels are in vivo composed of Kir6.2, a pore-forming ...
Cited by 30 - Related articles - BL Direct - All 8 versions

Glibenclamide-induced apoptosis is specifically enhanced by expression of the …

- aspetjournals.org
A Hambrock, CB de Oliveira Franz, S Hiller, … - Journal of Pharmacology and Experimental …, 2006 - ASPET
Sulfonylurea receptor 1 (SUR1) is the regulatory subunit of the pancreatic
ATP-sensitive K + channel (K ATP channel), which is essential for triggering
insulin secretion via membrane depolarization. Sulfonylureas, such as ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Comparative proteomic analysis for the detection of biomarkers in pancreatic ductal …


T Qi, J Han, Y Cui, M Zong, X Liu, B Zhu - British Medical Journal, 2008 - jcp.bmj.com
Results: A total of 48 differentially expressed proteins were identified; 30 of
them are novel potential biomarkers. Immunohistochemistry showed that TBX4
expression could be seen in both centroacinar cells and small ducts in ...
Cited by 10 - Related articles - BL Direct - All 3 versions

The role of incretins in glucose homeostasis and diabetes treatment

- nih.gov
W Kim, JM Egan - Pharmacological reviews, 2008 - ASPET
Cited by 11 - Related articles - All 5 versions

Role of KATP channels in protection against neuronal excitatory insults


MM Soundarapandian, X Zhong, L Peng, D Wu … - Journal of Neurochemistry, 2007 - interscience.wiley.com
ATP-sensitive K + (K ATP ) channels that are gated by intracellular ATP/ADP
concentrations are a unique subtype of potassium channels and play an essential
role in coupling intracellular metabolic events to electrical activity. ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human …

- physoc.org
G Kang, CA Leech, OG Chepurny, WA … - The Journal of physiology, 2008 - Physiological Soc
Protein kinase A (PKA)-independent actions of adenosine 3′,5′-cyclic
monophosphate (cAMP) are mediated by Epac, a cAMP sensor expressed in pancreatic
β-cells. Evidence that Epac might mediate the cAMP-dependent inhibition of ...
Cited by 6 - Related articles - BL Direct - All 6 versions


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