SA Hawley, DA Pan, KJ Mustard, L Ross, J … - Cell metabolism, 2005 - Elsevier The AMP-activated protein kinase (AMPK) is a critical regulator of energy
balance at both the cellular and whole-body levels. Two upstream kinases have
been reported to activate AMPK in cell-free assays, ie, the tumor ... Cited by 303 - Related articles - All 4 versions
- ►cell.com A Woods, K Dickerson, R Heath, SP Hong, M … - Cell Metabolism, 2005 - Elsevier AMP-activated protein kinase (AMPK) is the downstream component of a kinase
cascade that plays a pivotal role in energy homeostasis. Activation of AMPK
requires phosphorylation of threonine 172 (T172) within the T loop region ... Cited by 279 - Related articles - All 13 versions
- ►physiology.org TE Jensen, AJ Rose, SB Jorgensen, N Brandt, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc The Ca 2+ /calmodulin (CaM) competitive inhibitor KN-93 has previously been used
to evaluate 5'-AMP-activated protein kinase (AMPK)-independent Ca 2+ -signaling
to contraction-stimulated glucose uptake in muscle during intense ... Cited by 49 - Related articles - BL Direct - All 6 versions
KR Hallows - Current opinion in nephrology and hypertension, 2005 - journals.lww.com Purpose of review: It has long been recognized that the coupling of membrane
transport to underlying cellular metabolic status is critical because transport
processes consume a large portion of total cellular energy. Recently, the ... Cited by 32 - Related articles - BL Direct - All 8 versions
A Santana, R Ensenat-Waser, MI Arribas, JA … - Journal of Cellular and Molecular Medicine, 2006 - curemosladiabetes.com Type 1 diabetes is characterized by the selective destruction of pancreatic
ß-cells caused by an autoimmune attack. Type 2 diabetes is a more complex
pathology which, in addition to ß-cell loss caused by apoptotic programs, ... Cited by 25 - Related articles - View as HTML - BL Direct - All 5 versions
WW Winder, DM Thomson - Cell Biochemistry and Biophysics, 2007 - Springer Abstract AMP-activated protein kinase (AMPK) is an energy sensing/signaling
protein that, when activated, increases ATP production by stimulating glucose
uptake and fatty acid oxidation while at the same time inhibiting ATP ¼ ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►endocrinology-journals.org K Ravnskjaer, M Boergesen, LT Dalgaard, S … - Journal of molecular endocrinology, 2006 - Soc Endocrinology Tight regulation of fatty acid metabolism in pancreatic ß-cells is important
for ß-cell viability and function. Chronic exposure to elevated concentrations
of fatty acid is associated with ß-cell lipotoxicity. Glucose is known to ... Cited by 24 - Related articles - BL Direct - All 4 versions
F Diraison, E Motakis, LE Parton, GP Nason, I … - Diabetes, 2004 - Am Diabetes Assoc Accumulation of triglyceride in islets may contribute to the loss of
glucose-stimulated insulin secretion (GSIS) in some forms of type 2 diabetes
(Diraison et al., Biochem J 373:769–778, 2004). Here, we use adenoviral ... Cited by 21 - Related articles - BL Direct - All 4 versions
A Riboulet-Chavey, F Diraison, LK Siew, FS … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Clonal MIN6 β-cells or CD1 mouse pancreatic
islets were infected with recombinant adenoviruses encoding enhanced green
fluorescent protein (eGFP/null), constitutively active AMPK (AMPK-CA), or ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►physiology.org MA Raney, LP Turcotte - Journal of Applied Physiology, 2008 - Am Physiological Soc Calcium-calmodulin/dependent protein kinase II (CaMKII), AMP-activated protein
kinase (AMPK), and extracellular signal-regulated kinase (ERK1/2) have each been
implicated in the regulation of substrate metabolism during exercise. The ... Cited by 9 - Related articles - BL Direct - All 4 versions
