- ►endojournals.org AM Sharma, B Staels - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Conclusions: PPAR is highly expressed in adipose tissue, where its activation
with thiazolidinediones alters fat topography and adipocyte phenotype and
up-regulates genes involved in fatty acid metabolism and triglyceride ... Cited by 99 - Related articles - BL Direct - All 3 versions
- ►endojournals.org J Jager, T Grémeaux, M Cormont, Y Le … - Endocrinology, 2007 - Endocrine Soc Inflammation is associated with obesity and insulin resistance. Proinflammatory
cytokines produced by adipose tissue in obesity could alter insulin signaling
and action. Recent studies have shown a relationship between IL-1ß level ... Cited by 53 - Related articles - BL Direct - All 8 versions
- ►pubget.com [PDF] C Lagathu, L Yvan-Charvet, JP Bastard, M … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Adipose tissue inflammation has recently been
implicated in the pathogenesis of insulin resistance and is probably linked to
high local levels of cytokines. IL1B, a proinflammatory cytokine, may ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►shouxi.net CA Gysemans, L Ladrière, H Callewaert, J … - Diabetes, 2005 - Am Diabetes Assoc The main focus in studies on the pathogenesis of autoimmune type 1 diabetes has
been on the role of the immune system, with much less attention directed to the
target of the immune assault, namely the insulin-secreting β-cells. ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►shouxi.net K Laubner, TJ Kieffer, NT Lam, X Niu, F Jakob, … - Diabetes, 2005 - Am Diabetes Assoc Leptin inhibits insulin secretion and preproinsulin gene expression in
pancreatic β-cells, but signal transduction pathways and molecular mechanisms
underlying this effect are poorly characterized. In this study, we analyzed ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►endojournals.org R Salvi, E Castillo, MJ Voirol, M Glauser, JP … - Endocrinology, 2006 - Endocrine Soc Energy balance exerts a critical influence on reproduction via changes in the
circulating levels of hormones such as insulin. This modulation of the
neuroendocrine reproductive axis ultimately involves variations in the ... Cited by 18 - Related articles - BL Direct - All 4 versions
- ►shouxi.net SG Rønn, N Billestrup, T Mandrup-Poulsen - Diabetes, 2007 - Am Diabetes Assoc The pathogenesis of type 1 diabetes is not clearly understood, but it is
generally accepted that type 1 diabetes is an immune-mediated disease caused by
inflammation in the islets of Langerhans. Infiltrating macrophages release ... Cited by 15 - Related articles - BL Direct - All 4 versions
WB van den Berg, FAJ van de Loo - Arthritis & Rheumatism, 2006 - interscience.wiley.com Chondrocyte responsiveness to IGF-1 was assessed by 35 S-sulfate incorporation
into proteoglycans (PGs), via aggrecan messenger RNA expression, using
quantitative real-time polymerase chain reaction or insulin receptor ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►endojournals.org [PDF] J Jager, T Grémeaux, M Cormont, Y Le … - Endocrinology, 2006 - Endocrine Soc Page 1. - 1 - INTERLEUKIN-1β−INDUCED INSULIN RESISTANCE IN ADIPOCYTES
THROUGH DOWN-REGULATION OF IRS-1 EXPRESSION Running Title ... Cited by 6 - Related articles - All 2 versions
