- ►diabetesjournals.org EA Ryan, BW Paty, PA Senior, D Bigam, E Alfadhli, NM … - Diabetes, 2005 - Am Diabetes Assoc Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their mean
age was 42.9 ± 1.2 years, their mean duration of diabetes was 27.1 ± 1.3 years, and 57% ... Cited by 532 - Related articles - All 10 versions
- ►jimmunol.org TB Thornley, MA Brehm, TG Markees, LD … - The Journal of …, 2006 - Am Assoc Immnol Costimulation blockade protocols are effective in prolonging allograft survival in animal models
and are entering clinical trials, but how environmental perturbants affect graft survival remains
largely unstudied. We used a costimulation blockade protocol consisting of a ... Cited by 73 - Related articles - BL Direct - All 6 versions
- ►endocrinology-journals.org SK Richards, LE Parton, I Leclerc, GA Rutter, … - Journal of …, 2005 - Soc Endocrinology Treatment of type 1 diabetes by islet transplantation is currently limited by loss of functional
ß-cell mass after transplantation. We investigated here whether adenovirus-mediated changes
in AMP-activated protein kinase (AMPK) activity, previously shown to affect insulin ... Cited by 45 - Related articles - BL Direct - All 6 versions
- ►aspetjournals.org AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET Islet transplantation may be used to treat type I diabetes. Despite tremendous progress in islet
isolation, culture, and preservation, the clinical use of this modality of treatment is limited due
to post-transplantation challenges to the islets such as the failure to revascularize and ... Cited by 32 - Related articles - BL Direct - All 13 versions
T Eich, O Eriksson, T Lundgren… - The New England Journal of …, 2007 - nejm.highwire.org To the Editor: Although islet transplantation is an option for patients with type 1 diabetes, even
those who become insulin-independent after en- graftment have islet-graft function that is
esti- mated to be less than 30% of that in a healthy person. 1 In fact, most patients resume ... Cited by 27 - Related articles - All 3 versions
MR Rickels, MH Schutta, R Mueller, JF Markmann, CF … - Diabetes, 2005 - Am Diabetes Assoc Islet transplantation can eliminate severe hypoglycemic episodes in patients with type 1
diabetes; however, whether intrahepatic islets respond appropriately to hypoglycemia after transplantation
has not been fully studied. We evaluated six islet transplant recipients, six type 1 diabetic ... Cited by 23 - Related articles - BL Direct - All 5 versions
BW Paty, PA Senior, JRT Lakey, AMJ Shapiro, … - Diabetes Technology …, 2006 - liebertonline.com BREAY W. PATY, MD, 1,2 PETER A. SENIOR, MD, Ph.D., 1,2 ... JONATHAN RT LAKEY,
Ph.D., 2,3 AM JAMES SHAPIRO, MD, Ph.D., 2,3 ... Background: The aim of this study was to
assess and compare glycemic control using the con- tinuous glucose monitor (CGMS ® , ... Cited by 23 - Related articles - BL Direct - All 3 versions
F Bertuzzi, C Ricordi - Diabetes Care, 2007 - Am Diabetes Assoc Graft function prediction is a work in progress. Initially, the best parameters representative of
engrafted islet mass in recipients should be defined. Fasting C-peptide and exogenous insulin
requirements are commonly used, although other methods for a more complete ... Cited by 19 - Related articles - All 7 versions
PJ O Connell, WJ Hawthorne, DJ Holmes-Walker, … - Medical Journal of …, 2006 - mja.com.au Patients Patients eligible for selection for our study had had type 1 diabetes mellitus for more
that 5 years and were aged between 18 and 65 years. Additionally, they had recurrent severe
hypoglycaemia unawareness with coma that required constant monitoring or regular ... Cited by 17 - Related articles - View as HTML - BL Direct - All 5 versions
