R Desbriere, V Vuaroqueaux, V Achard, S … - Obesity, 2006 - nature.com Objective: Data from rodents provide evidence for a causal role of 11
-hydroxysteroid dehydrogenase type 1 (11 -HSD-1) in the development of obesity
and its complications. In humans, 11 -HSD-1 is increased in subcutaneous ... Cited by 34 - Related articles - All 3 versions
ME Symonds, DS Gardner - Current Opinion in Clinical Nutrition & Metabolic Care, 2006 - journals.lww.com Purpose of review: The developmental origins of adult disease represent a
burgeoning area of research for which it has been suggested that up to 50% of
the current incidence of later adult disease may be explained or even ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►physiology.org MG Gnanalingham, A Mostyn, ME Symonds, … - … Journal of Physiology- Regulatory, Integrative and …, 2005 - Am Physiological Soc Increased glucocorticoid action and adipose tissue inflammation contribute to
excess adiposity. These adaptations may be enhanced in offspring exposed to
nutrient restriction (NR) in utero, thereby increasing their susceptibility ... Cited by 20 - Related articles - BL Direct - All 4 versions
U Neitzke, T Harder, K Schellong, K … - Placenta, 2008 - Elsevier Research on intrauterine growth restriction (IUGR) and subsequent development of
obesity, type 2 diabetes and the metabolic syndrome is rapidly expanding, and
potential implications for primary prevention are considerable. We have ... Cited by 13 - Related articles - All 10 versions
- ►physiology.org P Darmon, F Dadoun, S Boullu-Ciocca, M … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Glucocorticoids hypersensitivity may be involved in the development of abdominal
obesity and insulin resistance. Eight normal weight and eight obese women
received on two occasions a 3-h intravenous infusion of saline or ... Cited by 12 - Related articles - BL Direct - All 3 versions
ME Symonds, T Stephenson, H Budge - American Journal of Clinical Nutrition, 2009 - Am Soc Nutrition It is now widely accepted that a gross change in the maternal diet during
pregnancy results in offspring with raised blood pressure. More recently,
results from human intervention studies and a range of animal experiments ... Cited by 10 - Related articles - All 6 versions
JC Jimenez-Chillaron, ME Patti - Current Opinion in Endocrinology, Diabetes and …, 2007 - journals.lww.com Purpose of review: Low birth weight and accelerated postnatal catch-up growth
during early life are independent risk factors for adult disease, including
diabetes, obesity, and cardiovascular disease. As they are intimately ... Cited by 10 - Related articles - BL Direct - All 2 versions
SF Witchel, DB DeFranco - Nature Reviews Endocrinology, 2006 - nature.com Glucocorticoids exert their effects in target tissues predominantly through
their interaction with the glucocorticoid receptor, a member of the nuclear
receptor superfamily of transcription factors. Over the years many studies ... Cited by 12 - Related articles - BL Direct - All 3 versions
JM Ordovas - American Journal of Clinical Nutrition, 2009 - Am Soc Nutrition Genetic polymorphism in human populations is part of the evolutionary process
that results from the interaction between the environment and the human genome.
Recent changes in diet have upset this equilibrium, potentially influencing ... Cited by 9 - Related articles - All 6 versions
