- ►jbc.org TL Martin, T Alquier, K Asakura, N Furukawa, F … - Journal of Biological …, 2006 - ASBMB AMP-activated protein kinase (AMPK) is a key regulator of cellular energy balance and of the
effects of leptin on food intake and fatty acid oxidation. Obesity is usually associated with resistance
to the effects of leptin on food intake and body weight. To determine whether diet-induced ... Cited by 53 - Related articles - BL Direct - All 7 versions
- ►cell.com B Kola, M Boscaro, GA Rutter, AB Grossman, M … - Trends in Endocrinology & …, 2006 - Elsevier Adenosine 5′ monophosphate-activated protein kinase (AMPK) is a regulator of cellular and
systemic energy homeostasis. It mediates some of the effects of peripheral hormones such as
leptin, ghrelin and adiponectin, and it is involved in the insulin-sensitizing role of the ... Cited by 49 - Related articles - All 9 versions
S Ramamurthy, GV Ronnett - The Journal of physiology, 2006 - Physiological Soc The 5′-adenosine monophosphate-activated protein kinase (AMPK) is a metabolic and stress
sensor that has been functionally conserved throughout eukaryotic evolution. Activation of the
AMPK system by various physiological or pathological stimuli that deplete cellular energy ... Cited by 41 - Related articles - BL Direct - All 9 versions
SM Han, C Namkoong, PG Jang, IS Park, SW Hong, H … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 2170–2178 DOI 10.1007/s00125-005-1913-1 ARTICLE S.-M.
Han . C. Namkoong . PG Jang . IS Park . SW Hong . H. Katakami . S. Chun . SW Kim . J.-Y. Park .
K.-U. Lee . M.-S. Kim Hypothalamic AMP-activated protein kinase mediates ... Cited by 30 - Related articles - BL Direct - All 3 versions
MS Kim, KU Lee - Journal of molecular medicine, 2005 - Springer Abstract Although obesity is an epidemic threat to general health worldwide, an effective treatment
has yetto befound. Insights into weight-regulatory pathways will accelerate the identification of
new molecular targets for anti-obesity agents. 5′-AMP-activated protein kinase (AMPK) ... Cited by 29 - Related articles - BL Direct - All 5 versions
- ►endojournals.org GR Steinberg, MJ Watt, BC Fam, J Proietto, S … - Endocrinology, 2006 - Endocrine Soc We examined the actions of a second-generation ciliary neurotrophic factor analog (CNTF Ax15
) on AMP-activated protein kinase (AMPK), a known regulator of food intake. Unlike leptin CNTF
Ax15 has been shown to reduce food intake in obese rodents and humans. ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org RJ McCrimmon, X Fan, H Cheng, E McNay, O Chan, M … - Diabetes, 2006 - Am Diabetes Assoc Defective counterregulatory responses (CRRs) to hypoglycemia are associated with a marked
increase in the risk of severe hypoglycemia. The mechanisms leading to the development of
defective CRRs remain largely unknown, although they are associated with antecedent ... Cited by 28 - Related articles - BL Direct - All 5 versions
PD Mountjoy, SJ Bailey, GA Rutter - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Changes in the activity of glucose-excited and glucose-inhibited neurons
within the basomedial hypothalamus are key to the central regulation of satiety. However, the
molecular mechanisms through which these cells respond to extracellular stimuli remain ... Cited by 25 - Related articles - BL Direct - All 6 versions
WW Winder, DM Thomson - Cell Biochemistry and Biophysics, 2007 - Springer Abstract AMP-activated protein kinase (AMPK) is an energy sensing/signaling protein that, when
activated, increases ATP production by stimulating glucose uptake and fatty acid oxidation while
at the same time inhibiting ATP ¼ consuming processes such as protein synthesis. ... Cited by 24 - Related articles - BL Direct - All 3 versions
- ►cell.com R Lage, C Diéguez, A Vidal-Puig, M López - Trends in Molecular Medicine, 2008 - Elsevier AMP-activated protein kinase (AMPK) is the downstream component of a kinase cascade that
acts as a gauge of cellular energy levels. Over the last few years, accumulating evidence has
demonstrated that AMPK is also involved in the regulation of energy balance at the whole- ... Cited by 14 - Related articles - All 7 versions
