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Scholar Results 1 - 10 of about 68 citing Devaraj: Hyperglycemia induces monocytic release of interleukin-6 via induction of protein.... (0.22 sec) 

The role of protein kinase C activation and the vascular complications of diabetes


N Das Evcimen, GL King - Pharmacological research, 2007 - Elsevier
Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in production
of insulin by the pancreas, and by resistance to insulin's effects. Such a deficiency results in increased
concentrations of glucose and other metabolites in the blood, which in turn damages ...
Cited by 64 - Related articles - All 4 versions

Lipid and lipoprotein dysregulation in insulin resistant states


RK Avramoglu, H Basciano, K Adeli - Clinica chimica acta, 2006 - Elsevier
Insulin resistant states are commonly associated with an atherogenic dyslipidemia that contributes
to significantly higher risk of atherosclerosis and cardiovascular disease. Indeed, disorders of
carbohydrate and lipid metabolism co-exist in the majority of subjects with the “metabolic ...
Cited by 58 - Related articles - All 3 versions

Direct demonstration of an antiinflammatory effect of simvastatin in subjects with …

- endojournals.org
S Devaraj, E Chan, I Jialal - Journal of Clinical Endocrinology & …, 2006 - Endocrine Soc
Context: Metabolic syndrome (MS) is characterized by low-grade inflammation and confers an
increased risk for cardiovascular disease. Hydroxymethylglutaryl coenzyme A reductase inhibitors
(statins) reduce cardiovascular events in MS patients. There is a paucity of data ...
Cited by 52 - Related articles - BL Direct - All 5 versions

Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation …


L Qi, RM van Dam, S Liu, M Franz, C Mantzoros, FB … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—After adjustment for age, BMI, lifestyle, and dietary covariates, intakes of whole grains
and bran were both associated with significantly decreasing trends of C-reactive protein
(CRP) (P for trend = 0.03 and 0.007, respectively) and tumor necrosis factor-α receptor 2 ( ...
Cited by 49 - Related articles - BL Direct - All 6 versions

Mechanisms of endothelial dysfunction in obesity


A Avogaro, SV de Kreutzenberg - Clinica Chimica Acta, 2005 - Elsevier
Obesity is a chronic disease, whose incidence is alarmingly growing, affecting not only adults
but also children and adolescents. It is associated with severe metabolic abnormalities and increased
cardiovascular morbidity and mortality. Adipose tissue secretes a great number of ...
Cited by 46 - Related articles - All 4 versions

Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK …

- diabetesjournals.org
F Homo-Delarche, S Calderari, JC Irminger, MN … - Diabetes, 2006 - Am Diabetes Assoc
The molecular pathways leading to islet fibrosis in diabetes are unknown. Therefore, we studied
gene expression in islets of 4-month-old Goto-Kakizaki (GK) and Wistar control rats. Of 71 genes
found to be overexpressed in GK islets, 24% belong to extracellular matrix (ECM)/cell ...
Cited by 45 - Related articles - BL Direct - All 6 versions

The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of …


T Wolever, AL Gibbs, C Mehling, JL … - American Journal of …, 2008 - ajcn.cnfindpark.cn
2 Supported by the Canadian Institutes of Health Research (CIHR-MCT-44205). Key foods were
donated by Kellogg Canada Inc, Robin Hood (division of Smucker Foods of Canada Co), HJ
Heinz Co, Italpasta Ltd, Uncle Ben's Rice (division of Mars Inc), Kraft Foods Inc, Dainty ...
Cited by 45 - Related articles - BL Direct - All 6 versions

Diabetes-enhanced inflammation and apoptosis--impact on periodontal pathology

- sagepub.com
DT Graves, R Liu, M Alikhani, H Al-Mashat, … - Journal of dental …, 2006 - jdr.sagepub.com
Cited by 33 - Related articles - BL Direct - All 3 versions

Inflammatory responses underlying the microvascular dysfunction associated with …


G Singer, DN Granger - Microcirculation, 2007 - informahealthcare.com
Obesity is a growing health care problem that is increasing the incidence and morbidity of cardiovascular
diseases. Emerging evidence suggests that obesity is associated with a systemic inflammatory
response that is characterized by endothelial cell dysfunction, oxidative stress, and the ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Molecular and signaling mechanisms of atherosclerosis in insulin resistance


EA Schwartz, PD Reaven - Endocrinology and metabolism clinics of North …, 2006 - Elsevier
It has long been appreciated that atherosclerosis is accelerated and the incidence of cardiovascular
disease (CVD) is higher in individuals with insulin resistance or type 2 diabetes mellitus [1] and
[2]. Although it is now clear that numerous risk factors, such as hyperglycemia, ...
Cited by 20 - Related articles - All 3 versions


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