CM García-Herrero, M Galan, O Vincent, B Flandez, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Glucokinase (GCK) acts as a glucose sensor in the pancreatic beta cell and
regulates insulin secretion. In the gene encoding GCK the heterozygous mutations that result in
enzyme inactivation cause MODY2. ... Cited by 13 - Related articles - BL Direct - All 5 versions
L Agius - Biochemical Journal, 2008 - eng.auburn.edu Conversion of glucose into glycogen is a major pathway that contributes to the removal of glucose
from the portal vein by the liver in the postprandial state. It is regulated in part by the increase
in blood-glucose concentration in ... Cited by 10 - Related articles - View as HTML - All 5 versions
- ►endojournals.org S Baltrusch, S Langer, L Massa, M Tiedge, S Lenzen - Endocrinology, 2006 - Endocrine Soc The glucose sensor enzyme glucokinase plays a pivotal role in the regulation of glucose-induced
insulin secretion in pancreatic ß-cells. Activation of glucokinase represents a promising concept
for the treatment of type 2 ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org S Baltrusch, M Tiedge - Diabetes, 2006 - Am Diabetes Assoc The low-affinity glucose-phosphorylating enzyme glucokinase (GK) is the flux-limiting glucose sensor
in liver and β-cells of the pancreas. Furthermore, GK is also expressed in various neuroendocrine
cell types. This review describes ... Cited by 6 - Related articles - BL Direct - All 4 versions
- ►physiology.org JS Shin, TP Torres, REL Catlin, EP … - American Journal of …, 2007 - Am Physiological Soc Effect of stimulation of glucokinase (GK) export from the nucleus by small amounts of sorbitol on
hepatic glucose flux in response to elevated plasma glucose was examined in 6-h fasted Zucker
diabetic fatty rats at 10 wk of ... Cited by 4 - Related articles - BL Direct - All 5 versions
S Baltrusch, S Lenzen - Diabetes, 2007 - Am Diabetes Assoc A stable MIN6 β-cell clone overexpressing glucokinase as an enhanced cyan fluorescent protein
(ECFP) fusion construct was generated for analysis of glucokinase regulation in these
glucose-responsive ... Cited by 3 - Related articles - BL Direct - All 5 versions
J Solera, P Arias, C Amiñoso, I González-Casado, … - Diabetes Research and …, 2009 - Elsevier Maturity onset diabetes of the young (MODY) is a genetically heterogeneous disorder characterized by
autosomal dominant inheritance, altered function of pancreatic beta cells and early onset diabetes
mellitus, usually before 25 years ... Cited by 2 - Related articles - All 16 versions
F Francini, MC Castro, JJ Gagliardino, … - Canadian Journal of …, 2009 - ingentaconnect.com Abstract: We evaluated the relative role of different regulatory mechanisms, particularly
6-phosphofructo-2-kinase/fruc- tose-2,6-biphosphatase (PFK2/FBPase-2), in liver glucokinase (GK)
activity in intact animals with ... Related articles - All 2 versions
S Baltrusch, S Lenzen - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Fluorescence microscopy opens new per- spectives for the analysis of
insulin secretory granule movement. In this study, we examined whether recently developed
photoactivatable/photoconvertible ... Related articles - BL Direct - All 2 versions