- ►jneurosci.org V Lukacs, B Thyagarajan, P Varnai, A Balla, T … - Journal of Neuroscience, 2007 - Soc Neuroscience The membrane phospholipid phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P 2
or PIP 2 ] regulates many ion channels. There are conflicting reports on the
effect of PtdIns(4,5)P 2 on transient receptor potential vanilloid 1 ... Cited by 53 - Related articles - All 6 versions
- ►jbc.org YW Lin, C MacMullen, A Ganguly, CA Stanley … - Journal of Biological Chemistry, 2006 - ASBMB The -cell ATP-sensitive potassium (K ATP ) channel controls insulin secretion by
linking glucose metabolism to membrane excitability. Loss of K ATP channel
function due to mutations in ABCC8 or KCNJ11, genes that encode the ... Cited by 34 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org AI Tarasov, CAJ Girard, FM Ashcroft - Diabetes, 2006 - Am Diabetes Assoc ATP-sensitive K + channels (K ATP channels) couple cell metabolism to electrical
activity and thereby to physiological processes such as hormone secretion,
muscle contraction, and neuronal activity. However, the mechanism by which ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►ox.ac.uk [PDF] S Haider, S Khalid, SJ Tucker, FM Ashcroft, … - Biochemistry, 2007 - pubs.acs.org Inward rectifier potassium (Kir) channels regulate cell excitability and
transport K + ions across membranes. Homotetrameric models of three mammalian
Kir channels (Kir1.1, Kir3.1, and Kir6.2) have been generated, using the ... Cited by 13 - Related articles - All 7 versions
- ►shouxi.net CW Lin, YW Lin, FF Yan, J Casey, M Kochhar, … - Diabetes, 2006 - Am Diabetes Assoc Heterozygous missense mutations in the pore-forming subunit Kir6.2 of
ATP-sensitive K + channels (K ATP channels) have recently been shown to cause
permanent neonatal diabetes mellitus (PNDM). Functional studies ... Cited by 12 - Related articles - BL Direct - All 5 versions
AJ García-Sáez, P Schwille - Applied microbiology and biotechnology, 2007 - Springer Abstract Single molecule techniques promise novel infor- mation about the
properties and behavior of individual particles, thus enabling access to
molecular heterogeneities in biological systems. Their recent developments ... Cited by 10 - Related articles - BL Direct - All 7 versions
DU Schulze, M Düfer, B Wieringa, P Krippeit … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis In a previous study, we demonstrated that a creatine
kinase (CK) modulates K ATP channel activity in pancreatic beta cells. To
explore phosphotransfer signalling pathways in more detail, we examined ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org FF Yan, YW Lin, C MacMullen, A Ganguly, CA … - Diabetes, 2007 - Am Diabetes Assoc Congenital hyperinsulinism (CHI) is a disease characterized by persistent
insulin secretion despite severe hypoglycemia. Mutations in the pancreatic
ATP-sensitive K + (K ATP ) channel proteins sulfonylurea receptor 1 (SUR1) ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►nih.gov YW Lin, JD Bushman, FF Yan, S Haidar, C … - Journal of Biological Chemistry, 2008 - ASBMB The inwardly rectifying potassium channel Kir6.2 is the pore-forming subunit of
the ATP-sensitive potassium (K ATP ) channel, which controls insulin secretion
by coupling glucose metabolism to membrane potential in β-cells. Loss of ... Cited by 4 - Related articles - All 4 versions
- ►shouxi.net S Thore, A Wuttke, A Tengholm - Diabetes, 2007 - Am Diabetes Assoc Phosphatidylinositol-4,5-bisphosphate (PIP 2 ) is important for a variety of
cellular processes as a precursor for second messengers and by regulating ion
channels, the cytoskeleton, and vesicle traffic in many types of cells, ... Cited by 5 - Related articles - BL Direct - All 6 versions
