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Scholar Results 1 - 10 of about 35 citing Noguchi: BETA2/NeuroD protein can be transduced into cells due to an arginine-and lysine-rich.... (0.13 sec) 

[PDF] Protein transduction technology: a novel therapeutic perspective


H Noguchi, S Matsumoto - Acta Medica Okayama, 2006 - lib.okayama-u.ac.jp
The direct intracellular delivery of proteins has, until recently, been difficult to achieve, due
primar- ily to the bioavailability barrier of the plasma membrane. During the past 15 years, a variety
of peptides called protein transduction domains (PTDs) or cell penetrating peptides ...
Cited by 49 - Related articles - View as HTML - BL Direct - All 8 versions

Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet …


H Noguchi, M Ueda, Y Nakai, Y Iwanaga, … - American Journal of …, 2006 - interscience.wiley.com
Islet allotransplantation can achieve insulin independence in patients with type I diabetes. Recent
reports show that the two-layer method (TLM), which employs oxygenated perfluorochemical
(PFC) and UW solution, is superior to simple cold storage in UW for pancreas ...
Cited by 24 - Related articles - BL Direct - All 7 versions

Cell-surface proteoglycans as molecular portals for cationic peptide and polymer …


G Poon, J Gariepy - Biochemical Society Transactions, 2007 - biochemsoctrans.org
Polycationic macromolecules and cationic peptides acting as PTDs (protein transduction
domains) and CPPs (cell-penetrating peptides) represent important classes of agents used for
the import and delivery of a wide range of molecular cargoes into cells. Their entry into ...
Cited by 23 - Related articles - Cached - BL Direct - All 4 versions

Activation of c-Jun NH 2-terminal kinase (JNK) pathway during islet transplantation …


H Noguchi, Y Nakai, M Ueda, Y Masui, S Futaki, N … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Activation of c-Jun NH 2 -terminal kinase (JNK) pathway during islet
transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor H. Noguchi
& Y. Nakai & M. Ueda & Y. Masui & S. Futaki & N. Kobayashi & S. Hayashi & S. Matsumoto ...
Cited by 15 - Related articles - BL Direct - All 6 versions

Stem/progenitor cell sources of insulin-producing cells for the treatment of diabetes

- duke.edu [PDF] 
LT Lock, ES Tzanakakis - Tissue Engineering, 2007 - liebertonline.com
Patients with diabetes experience decreased insulin secretion that is linked to a significant reduction
in the number of islet cells. Reversal of diabetes can be achieved through islet
transplantation, but the scarcity of donor islets severely hinders wide application of this ...
Cited by 16 - Related articles - BL Direct - All 5 versions

Protein transduction technology offers a novel therapeutic approach for diabetes


H Noguchi, S Matsumoto - Journal of Hepato-Biliary-Pancreatic Surgery, 2006 - Springer
1 Diabetes Research Institute Kyoto, Kyoto, Japan 2 Research Fellow of the Japan Society for
the Promotion of Science (SPD), Kyoto, Japan 3 Department of Transplantation and
Immunology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapy


M Liu, ZC Han - J Cell Mol Med, 2008 - interscience.wiley.com
Mesenchymal stem cells (MSCs) can be derived from adult bone marrow, fat and several foetal
tissues. In vitro, MSCs have the capacity to differentiate into multiple mesodermal and non-mesodermal
cell lineages. Besides, MSCs possess immunosuppressive effects by modulating the ...
Cited by 14 - Related articles - All 3 versions

A novel type of PTD, common helix–loop–helix motif, could efficiently mediate …


J Chen, G Li, J Lu, L Chen, Y Huang, H Wu, J … - … and Biophysical Research …, 2006 - Elsevier
Protein transduction domains (PTDs), such as HIV TAT PTD, have been widely used as delivery
tools into living cells. Here we reported for the first time that the helix–loop–helix (HLH) domain
of basic helix–loop–helix (bHLH) family was a novel type of PTD. Efficient internalization ...
Cited by 13 - Related articles - All 5 versions

Pancreatic islet transplantation for treating diabetes

- psu.edu [PDF] 
S Matsumoto, H Noguchi, Y Yonekawa, T … - Expert Opin. Biol. …, 2006 - informahealthcare.com
Pancreatic islet transplantation is one of the options for treating diabetes and has been shown
to improve the quality of life of severe diabetic patients. Since the Edmonton protocol was
announced, islet transplantation have advanced considerably, including islet after kidney ...
Cited by 12 - Related articles - BL Direct - All 8 versions

Evaluation of islet transplantation from non-heart beating donors.


H Noguchi, Y Iwanaga, T Okitsu, H Nagata, Y … - American Journal of …, 2006 - ccmjournal.org
O ver the last few decades, we have witnessed numerous re- search findings and new tech-
nologies that help us provide better care to our patients. Unfortunately, the quality of health care
is far from opti- mal (1). There have been urgent calls high- lighting the need to close the ...
Cited by 10 - Related articles - BL Direct - All 6 versions


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