- ►ucla.edu [PDF] CE Murry, G Keller - Cell, 2008 - Elsevier The potential to generate virtually any differentiated cell type from embryonic stem cells
(ESCs) offers the possibility to establish new models of mammalian development and to create
new sources of cells for regenerative medicine. To realize this potential, it is essential to ... Cited by 129 - Related articles - All 14 versions
- ►alphamedpress.org J Jiang, M Au, K Lu, A Eshpeter, G Korbutt, G Fisk, AS … - Stem Cells, 2007 - AlphaMed Press Recent success in pancreatic islet transplantation has energized the field to discover an alternative
source of stem cells with differentiation potential to ß cells. Generation of
glucose-responsive, insulin-producing ß cells from self-renewing, pluripotent human ... Cited by 96 - Related articles - BL Direct - All 7 versions
- ►endojournals.org A Trounson - Endocrine reviews, 2006 - Endocrine Soc Human embryonic stem cells (hESCs) are being rapidly produced from chromosomally
euploid, aneuploid, and mutant human embryos that are available from in vitro fertilization clinics
treating patients for infertility or preimplantation genetic diagnosis. These hESC lines are ... Cited by 91 - Related articles - BL Direct - All 6 versions
- ►alphamedpress.org M Mimeault, SK Batra - Stem Cells, 2006 - AlphaMed Press In this study, we report on recent advances on the functions of embryonic, fetal, and adult stem
cell progenitors for tissue regeneration and cancer therapies. We describe new procedures for
derivation and maturation of these stem cells into the tissue-specific cell progenitors. The ... Cited by 78 - Related articles - BL Direct - All 9 versions
- ►calvin.edu [PDF] Y Zhao, H Wang, T Mazzone - Experimental cell research, 2006 - Elsevier We identified stem cells from the umbilical cord blood, designated cord blood–stem cells
(CB–SC). CB–SC displayed important embryonic stem (ES) cell characteristics including expression
of ES-cell-specific molecular markers including transcription factors OCT-4 and Nanog, ... Cited by 60 - Related articles - All 7 versions
JH Shim, SE Kim, DH Woo, SK Kim, CH Oh, R McKay, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Directed differentiation of human embryonic stem cells towards
a pancreatic cell fate JH Shim & SE Kim & DH Woo & SK Kim & CH Oh & R. McKay
& JH Kim Received: 3 July 2006 /Accepted: 15 January 2007 ... Cited by 48 - Related articles - BL Direct - All 5 versions
W Jiang, Y Shi, D Zhao, S Chen, J Yong, J Zhang, T … - Cell Research, 2007 - nature.com The capacity for self-renewal and differentiation of human embryonic stem (ES) cells makes them
a potential source for generation of pancreatic beta cells for treating type I diabetes mellitus.
Here, we report a newly developed and effective method, carried out in a serum-free ... Cited by 46 - Related articles - BL Direct - All 7 versions
- ►ucla.edu [PDF] JJ MEIER, A BHUSHAN, PC BUTLER - Pediatric research, 2006 - journals.lww.com Both type 1 and type 2 diabetes are characterized by a marked deficit in beta-cell mass causing
insufficient insulin secretion. Beta-cell replacement strategies may eventually provide a cure
for diabetes. Current therapeutic approaches include pancreas and islet transplantation, ... Cited by 33 - Related articles - BL Direct - All 7 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative lack of insulin-producing
β cells, respectively. Reconstitution of a functional β-cell mass by cell therapy – using organ donor
islets of Langerhans – has been demonstrated to restore euglycaemia in the absence of ... Cited by 27 - Related articles - BL Direct - All 6 versions
