- ►cell.com J Greenwood, JC Mason - Trends in immunology, 2007 - Elsevier Statins reduce cholesterol synthesis and are widely used for the treatment of hyperlipidaemia
and ischaemic heart disease. Besides their cholesterol-lowering effects, statins also possess
broad immunomodulatory and anti-inflammatory properties. Vascular endothelial cells ... Cited by 34 - Related articles - All 5 versions
J Chen, M Chopp - NeuroRx, 2006 - Elsevier There is a compelling need to develop cell and pharmacological therapeutic approaches to be
administered beyond the hyperacute phase of stroke. These therapies capitalize on the capacity
of the brain for neuroregeneration and neuroplasticity and are designed to reduce ... Cited by 28 - Related articles - All 14 versions
BT Hawkins, TF Lundeen, KM Norwood, HL Brooks, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Although diabetes mellitus is associated with peripheral microvascular
complications and increased risk of neurological events, the mechanisms by which diabetes
disrupts the blood–brain barrier (BBB) are not known. Matrix metalloproteinase (MMP) ... Cited by 22 - Related articles - BL Direct - All 6 versions
- ►uni-mainz.de [PDF] CRW Kuhlmann, V Lessmann, HJ Luhmann - Neuropharmacology, 2006 - Elsevier Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme-A reductase and the downstream mevalonate
pathway is in part responsible for the beneficial effects that statins exert on the cardiovascular
system. In this study we aimed at analysing the stabilizing effects of fluvastatin on the ... Cited by 12 - Related articles - All 5 versions
JT Maikos, DI Shreiber - Journal of Neurotrauma, 2007 - liebertonline.com Primary damage to the blood–spinal cord barrier (BSCB) is a nearly universal consequence
of spinal cord injury that contributes significantly to the overall pathology, including the introduction
of re- active species that induce cytotoxicity as well as secondary insults on the BSCB ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►iovs.org M Al-Shabrawey, M Bartoli, AB El-Remessy, G Ma, S … - … Ophthalmology & Visual …, 2008 - ARVO PURPOSE. Inhibitors of 3-hydroxy-3-methylglutaryl CoA reductase (statins) reduce signs of diabetic
retinopathy in diabetic patients and animals. Indirect clinical evidence supports the actions of
statins in improving cardiovascular function, but the mechanisms of their protective ... Cited by 12 - Related articles - All 3 versions
C Vecchione, MT Gentile, A Aretini, G Marino, R Poulet, … - Diabetologia, 2007 - Springer Page 1. ARTICLE A novel mechanism of action for statins against diabetes-induced
oxidative stress C. Vecchione & MT Gentile & A. Aretini & G. Marino & R. Poulet &
A. Maffei & F. Passarelli & A. Landolfi & A. Vasta & G. Lembo ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org MJ Haas, MH Horani, SA Parseghian, AD Mooradian - Diabetes, 2006 - Am Diabetes Assoc Statins may have favorable effects on endothelial barrier function, possibly through reduction
of oxidative stress and modulation of expression of vasoactive proteins. The permeability of human
umbilical endothelial cells in culture to a group of fluorescein isothiocyanate dextrans of ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►nih.gov BT Hawkins, SM Ocheltree, KM Norwood, RD Egleton - Neuroscience letters, 2007 - Elsevier Investigations of the blood–brain barrier (BBB) in diabetes have yielded contradictory
results. It is possible that diabetes differentially affects paracellular and transcellular permeabilities
via modulation of tight junction and transport proteins, respectively. Fluorescein (FL), a ... Cited by 7 - Related articles - All 4 versions
C Gustavsson, CD Agardh, P Hagert, E Agardh - Retina, 2008 - journals.lww.com Supported by grants from the Lund University, the Järnhardt Foundation, the Malmö University
Hospital Foundation, the Stoltz Foundation, the Foundation for Visually Impaired in Former Malmöhus
Län, the Skane County Council for Research and Development, the Swedish Diabetes ... Cited by 6 - Related articles - BL Direct - All 2 versions
