MMJ Combettes - Current opinion in pharmacology, 2006 - Elsevier The first antidiabetic treatment (exenatide; Byetta) based on the incretin hormone glucagon-like
peptide-1 (GLP-1) was approved in 2005 as an adjunctive therapy in diabetic patients in whom
sulfonylurea, metformin or both had failed. Many GLP-1 mimetics or dipeptidyl peptidase ... Cited by 15 - Related articles - All 3 versions
MJ Kim, Y Rolland, O Cepeda, JK Gammack, JE … - The Aging …, 2006 - informahealthcare.com Most persons with diabetes mellitus are over the age of 60 years. Males develop diabetes more
commonly than females. Older diabetics tend to have both impaired insulin release as well as
insulin resistance. In older persons diabetes mellitus is associated with decreased ... Cited by 14 - Related articles - BL Direct - All 6 versions
M Combettes, C Kargar - Therapie, 2007 - edpsciences. org Abstract – Type 2 diabetes is an endocrine/metabolic disease characterized by
hyperglycemia. It is now well established that insulin resistance and pancreatic β-cell
dysfunction/failure are the two major components of the physiopathology of the disease. ... Cited by 10 - Related articles - All 3 versions
BG Szczepankiewicz, R … - Current Topics in Medicinal …, 2007 - ingentaconnect.com Abstract: Xanthines and xanthine-like DPP-IV inhibitors were first disclosed in 2002. Since
then, several dozen accounts of xanthine-based DPP-IV inhibitors have been published. Only
a few presentations and journal articles have appeared, with the vast majority of ... Cited by 1 - Related articles - BL Direct - All 2 versions
II Gwaltney, L Stephen - Current Topics in Medicinal Chemistry, 2008 - ingentaconnect.com Abstract: Inhibitors of dipeptidyl peptidase IV (DPP-4) have emerged as an important new class
of therapeutic agents for type two diabetes. Various medicinal chemistry approaches have been
applied to this area and have resulted in the identification of numerous late-stage ... Related articles - All 2 versions
- ►nih.gov HM Cox - Nutrition, 2008 - Elsevier Y 1 and Y 2 tones were present in human and WT mouse colon mucosa and only the latter was
TTX sensitive. Y 1 tone was unchanged in NPY −/− but was 90% inhibited in PYY −/− and abolished
in PYYNPY −/− colon mucosa. Y 2 tone was reduced 50% in NPY −/− and PYY −/− ... Related articles - All 6 versions
N Approved, PA Agents - Thérapie, 2007 - ogst.ifp.fr Abstract – Type 2 diabetes is an endocrine/metabolic disease characterized by
hyperglycemia. It is now well established that insulin resistance and pancreatic β-cell
dysfunction/failure are the two major components of the physiopathology of the disease. ... Related articles - All 2 versions