T Tsuchiya, PEH Schwarz, L del Bosque-Plata, MG … - Molecular Genetics and …, 2006 - Elsevier We conducted pooled and meta-analyses of the association of the calpain-10 gene
(CAPN10) polymorphisms SNP-43, Indel-19 and SNP-63 individually and as haplotypes with
type 2 diabetes (T2D) in 3237 patients and 2935 controls of European ancestry. In the ... Cited by 40 - Related articles - All 3 versions
H Fujita, T Nedachi, M Kanzaki - Experimental cell research, 2007 - Elsevier The assembly of sarcomeres, the smallest contractile units in striated muscle, is a complex and
highly coordinated process that relies on spatio-temporal organization of sarcomeric
proteins, a process requiring spontaneous Ca 2+ transients. To investigate the ... Cited by 17 - Related articles - All 4 versions
J Pihlajamäki, U Salmenniemi, M Vänttinen, E … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: The mechanisms by which the calpain-10 gene (CAPN10) affects
the risk of type 2 diabetes are unclear. Therefore, we investigated the effects of four polymorphisms
in CAPN10 (single nucleotide polymorphism [SNP]-43, SNP-44, Insertion/Deletion ... Cited by 14 - Related articles - BL Direct - All 5 versions
L Norton, T Parr, RG Bardsley, H Ye, K … - Acta …, 2007 - viking.nottingham.ac.uk Received 4 September 2006, revision requested 5 October 2006, revision received 10 October
2006, accepted 10 October 2006 Correspondence: Dr K. Tsintzas, School of Biomedical
Sciences, Nottingham University Medical School, Queen's Medical Centre, Nottingham ... Cited by 7 - Related articles - View as HTML - BL Direct - All 6 versions
AE Brown, SJ Yeaman, M Walker - Molecular Genetics and Metabolism, 2007 - Elsevier Calpain-10 was identified as a novel type 2 diabetes susceptibility gene, although the mechanisms
by which it increases susceptibility to type 2 diabetes remain unclear. As skeletal muscle is the
principal site of the peripheral insulin resistance for glucose disposal in type 2 diabetes, ... Cited by 7 - Related articles - All 3 versions
F Harris, S Biswas, J Singh, S Dennison, … - ANNALS-NEW YORK …, 2006 - interscience.wiley.com Abstract: Type 2 diabetes mellitus (T2DM) can lead to death without treatment and it has been
predicted that the condition will affect 215 million people worldwide by 2010. T2DM is a multifactorial
disorder whose precise genetic causes and biochemical defects have not been fully ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►eje-online.org N Zhang, YH Shi, CF Hao, HF Gu, Y Li, YR Zhao, LC … - European Journal of …, 2008 - EFES Results: Both SNPs were found to be significantly associated with PCOS (P=0.021, odds
ratios=1.629, 95% confidence intervals: 1.074–2.469 and P=0.015, 1.576, 1.091–2.279
respectively). In SNP +276(G/T), the allele G was found to be significantly associated with ... Cited by 8 - Related articles - BL Direct - All 7 versions
L Groop, V Lyssenko - Current diabetes reports, 2008 - Springer In 2007, five whole genome–wide association stud- ies were published on the genetics of type
2 diabetes mellitus (T2DM), followed by the discovery of 11 genes consistently associated with
T2DM. This breakthrough provided the first glimpses of a complete picture of the ... Cited by 5 - Related articles - All 2 versions
E López-Orduña, J García-Mena, R García-Macedo … - … and Biophysical Research …, 2007 - Elsevier The mRNA concentration of CAPN10, a T2D susceptibility gene was measured in white blood
cells of T2D and healthy subjects, as well as the transcript half-life in two SNP-43 genotyped
human cell lines, to evaluate a possible relationship between this SNP-43 and the ... Cited by 5 - Related articles - All 5 versions
M Ridderstråle, E Nilsson - Current Hypertension Reports, 2008 - Springer CAPN10, which encodes the cysteine protease calpain 10, was the first type 2 diabetes mellitus
(T2DM) sus- ceptibility gene identified through a genome-wide scan followed by positional
cloning. A haplotype combina- tion comprising three intronic CAPN10 single-nucleotide ... Cited by 3 - Related articles - BL Direct - All 2 versions
