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Scholar Results 1 - 10 of about 23 citing Rose: A 30G A polymorphism of the-cell–specific glucokinase promoter associates with hyperglyce.... (0.17 sec) 

Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) …

- diabetesjournals.org
W Winckler, MN Weedon, RR Graham, SA … - Diabetes, 2007 - Am Diabetes Assoc
An important question in human genetics is the extent to which genes causing
monogenic forms of disease harbor common variants that may contribute to the
more typical form of that disease. We aimed to comprehensively evaluate the ...
Cited by 56 - Related articles - BL Direct - All 5 versions

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: …

- nih.gov
MN Weedon, VJ Clark, Y Qian, Y Ben-Shlomo, N … - The American Journal of Human Genetics, 2006 - Elsevier
Fasting glucose is associated with future risk of type 2 diabetes and ischemic
heart disease and is tightly regulated despite considerable variation in
quantity, type, and timing of food intake. In pregnancy, maternal fasting ...
Cited by 35 - Related articles - BL Direct - All 13 versions

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

- diabetesjournals.org
M Vaxillaire, J Veslot, C Dina, C Proença, S … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The GCK (Glucokinase) −30A allele was associated with increased
type 2 diabetes risk at the end of the follow-up study (adjusted OR 1.34 [95% CI
1.07–1.69]) under an additive model, as supported in independent French ...
Cited by 34 - Related articles - BL Direct - All 4 versions

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels


WM Chen, MR Erdos, AU Jackson, R Saxena, S … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov
1 Department of Public Health Sciences and 2 Center for Public Health Genomics,
University of Virginia, Charlottesville, Virginia, USA. 3 Genome Technology
Branch, National Human Genome Research Institute, Bethesda, Maryland, USA. ...
Cited by 25 - Related articles - All 21 versions

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, …


T Sparsø, G Andersen, T Nielsen, KS … - Diabetologia, 2008 - Springer
Page 1. ARTICLE The GCKR rs780094 polymorphism is associated with elevated
fasting serum triacylglycerol, reduced fasting and OGTT ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Common variants in MODY genes increase the risk of gestational diabetes mellitus


N Shaat, E Karlsson, Å Lernmark, S Ivarsson, … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 1545–1551 DOI 10.1007/s00125-006-0258-8 ARTICLE
N. Shaat . E. Karlsson . Å. Lernmark . S. Ivarsson . K. Lynch . H. Parikh . ...
Cited by 20 - Related articles - BL Direct - All 6 versions

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 …

- diabetesjournals.org
J Holmkvist, P Almgren, V Lyssenko, CM … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—The polymorphism rs1169288 in HNF-1α strongly predicted future type 2
diabetes (hazard ratio [HR] 1.2, P = 0.0002). Also, SNPs rs4810424 and rs3212198
in HNF-4α nominally predicted future type 2 diabetes (HR 1.3 [95% CI ...
Cited by 18 - Related articles - All 3 versions

A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased …


N Shaat, Å Lernmark, E Karlsson, S Ivarsson, … - Diabetologia, 2007 - Springer
Page 1. ARTICLE A variant in the transcription factor 7-like 2 (TCF7L2) gene is
associated with an increased risk of gestational diabetes mellitus ...
Cited by 11 - Related articles - BL Direct - All 3 versions

A new era in finding Type 2 diabetes genes-the unusual suspects


TM Frayling - Diabetic Medicine, 2007 - interscience.wiley.com
In 1988 the task of identifying Type 2 diabetes genes was described as a
nightmare. For the next 17 years this proved to be largely correct. In the
meantime the prevalence of Type 2 diabetes rose sharply due to non-genetic ...
Cited by 12 - Related articles - All 3 versions

Insights on pathogenesis of type 2 diabetes from MODY genetics


MN Weedon, TM Frayling - Current Diabetes Reports, 2007 - Springer
Introduction Maturity-onset diabetes of the young (MODY) is a type of
non–insulin-dependent diabetes mellitus caused by rare autosomal-dominant
mutations, accounting for 1% to 2% of diabetes cases. Patients with MODY ...
Cited by 2 - Related articles - BL Direct - All 2 versions


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