V Puri, S Ranjit, S Konda, S Nicoloro, J … - Proceedings of the …, 2008 - National Acad Sciences Storage of energy as triglyceride in large adipose-specific lipid droplets is a fundamental need
in all mammals. Efficient sequestration of fat in adipocytes also prevents fatty acid overload in
skeletal muscle and liver, which can impair insulin signaling. Here we report that the Cide ... Cited by 33 - Related articles - BL Direct - All 9 versions
- ►jbc.org P Keller, JT Petrie, P De Rose, I Gerin, WS Wright, … - Journal of Biological …, 2008 - ASBMB FSP27 (fat-specific protein 27) is a member of the cell death-inducing DNA fragmentation
factor- -like effector (CIDE) family. Although Cidea and Cideb were initially characterized as activators
of apoptosis, recent studies have demonstrated important metabolic roles for these ... Cited by 22 - Related articles - All 4 versions
- ►endojournals.org A Gummesson, M Jernas, PA Svensson, I … - Journal of Clinical …, 2007 - Endocrine Soc Results: The CIDEA gene was predominantly expressed in adipocytes as compared with other
human tissues. CIDEA gene expression in adipose tissue was inversely associated with basal
metabolic rate independently of body composition, age, and gender (P = 0.014). The ... Cited by 19 - Related articles - BL Direct - All 2 versions
JZ Li, J Ye, B Xue, J Qi, J Zhang, Z Zhou, Q Li, Z Wen, P … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Our previous study suggests that Cidea, a member of Cide family proteins that
share sequence homology with the DNA fragmentation factor and are expressed at high levels
in brown adipose tissue, plays an important role in the development of obesity. Cideb, ... Cited by 18 - Related articles - BL Direct - All 6 versions
I Dahlman, P Arner - International Journal of Obesity, 2007 - nature.com Obesity is the result of an imbalance between food intake and energy expenditure resulting in
the storing of energy as fat. Adipose tissue contains the largest store of energy in the body and
plays important roles in regulating energy partitioning. Developments in genomics, in ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►nih.gov M Hallberg, DL Morganstein, E Kiskinis, K … - Molecular and Cellular …, 2008 - Am Soc Microbiol Nuclear receptors activate or repress target genes depending on the recruitment of coactivators
or corepressors. The corepressor RIP140 and the PPAR coactivator 1 (PGC-1 ) both play key
roles in the regulated transcription of genes involved in energy homeostasis. We ... Cited by 11 - Related articles - All 6 versions
J Qi, J Gong, T Zhao, J Zhao, P Lam, J Ye, JZ … - The EMBO …, 2008 - pubmedcentral.nih.gov We previously showed that Cidea −/− mice are resistant to diet-induced obesity through the upregulation
of energy expenditure. The AMP-activated protein kinase (AMPK), consisting of catalytic α subunit
and regulatory subunits β and γ, has a pivotal function in energy homoeostasis. We show ... Cited by 12 - Related articles - BL Direct - All 5 versions
V Puri, MP Czech - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Fat-specific protein of 27 kDa (FSP27) is a highly expressed adipocyte protein that promotes
triglyceride accumulation within lipid droplets. In this issue of the JCI, Nishino et al. show that
FSP27 also helps to maintain the characteristically large unilocular lipid droplet structure ... Cited by 10 - Related articles - All 9 versions
- ►physiology.org JY Kim, K Liu, S Zhou, K Tillison, Y Wu, … - American Journal of …, 2008 - Am Physiological Soc Fat-specific protein 27 (FSP27)/CIDEC was initially identified by its upregulation in TA1 adipogenesis
and is one of three cell death-inducing DFF45-like effector (CIDE) family proapoptotic
proteins. Ectopic expression of CIDEs promotes apoptosis of mammalian cells. On the ... Cited by 8 - Related articles - BL Direct - All 3 versions
- ►aacrjournals.org J Laurencikiene, BM Stenson, E Arvidsson Nordstrom, … - Cancer Research, 2008 - AACR Cancer cachexia is associated with poor survival rate and impaired response to chemotherapy
(1, 2). It is characterized by loss of both adipose tissue and skeletal muscle (1, 2). The former
often precedes and is more rapid than the latter (3). Several factors may induce loss of ... Cited by 8 - Related articles - All 2 versions
