CG Nichols - Nature, 2006 - nature.com Even in the absence of ATP, the single-channel kinetics of K ATP are complex,
but certain key features are clearly discernible and can be modelled by assuming
a single 'fast' gate and ligand-operated 'slow' gates within each subunit ... Cited by 136 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org M Vaxillaire, A Dechaume, K Busiah, H Cavé, … - Diabetes, 2007 - Am Diabetes Assoc Activating mutations in the ABCC8 gene that encodes the sulfonylurea receptor 1
(SUR1) regulatory subunit of the pancreatic islet ATP-sensitive K + channel (K
ATP channel) cause both permanent and transient neonatal diabetes. ... Cited by 24 - Related articles - BL Direct - All 6 versions
K Balogh, K Rácz, A Patócs, L Hunyady - Trends in Endocrinology & Metabolism, 2006 - Elsevier The multiple endocrine neoplasia type 1 (MEN1) gene is a tumor suppressor gene
encoding a 610 amino acid nuclear protein, menin. Although mutations of the MEN1
gene are responsible for MEN 1 syndrome, the intracellular functions of ... Cited by 23 - Related articles - All 6 versions
- ►endojournals.org YM Leung, EP Kwan, B Ng, Y Kang, HY … - Endocrine reviews, 2007 - Endocrine Soc The three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein
receptor) proteins, syntaxin, SNAP25 (synaptosome-associated protein of 25 kDa),
and synaptobrevin, constitute the minimal machinery for exocytosis in ... Cited by 16 - Related articles - BL Direct - All 3 versions
- ►shouxi.net CW Lin, YW Lin, FF Yan, J Casey, M Kochhar, … - Diabetes, 2006 - Am Diabetes Assoc Heterozygous missense mutations in the pore-forming subunit Kir6.2 of
ATP-sensitive K + channels (K ATP channels) have recently been shown to cause
permanent neonatal diabetes mellitus (PNDM). Functional studies ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org P Dewint, V Gossye, K De Bosscher, W … - The Journal of Immunology, 2008 - Am Assoc Immnol The glucocorticoid receptor (GR) is a transcription factor regulating its target
genes either positively, through direct binding to the promoter of target genes,
or negatively by the interference with the activity of transcription ... Cited by 11 - Related articles - All 3 versions
- ►tokushima-u.ac.jp [PDF] Y Sakamoto, H Inoue, P Keshavarz, K … - Journal of Human Genetics, 2007 - Springer Abstract Many genetic association studies support a contribution of genetic
variants in the KCNJ11-ABCC8 gene locus to type 2 diabetes (T2D) susceptibility
in Caucasians. In non-Caucasian populations, however, there have been only ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JC Koster, MS Remedi, R Masia, B Patton, A … - Diabetes, 2006 - Am Diabetes Assoc Glucose metabolism in pancreatic β-cells elevates cytoplasmic [ATP]/[ADP],
causing closure of ATP-sensitive K + channels (K ATP channels), Ca 2+ entry
through voltage-dependent Ca 2+ channels, and insulin release. Decreased ... Cited by 9 - Related articles - BL Direct - All 5 versions
JC Jimenez-Chillaron, E Isganaitis, M … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE—Low birth weight (LBW) is associated with increased risk of obesity,
diabetes, and cardiovascular disease during adult life. Moreover, this
programmed disease risk can progress to subsequent generations. We ... Cited by 4 - Related articles - All 3 versions
- ►jbc.org Z Gan, L Zhao, L Yang, P Huang, F Zhao, W Li … - Journal of Biological Chemistry, 2006 - ASBMB RNA editing via the conversion of adenosine (A) to inosine (I) is catalyzed by
two major families of adenosine deaminases acting on RNA (ADARs), ADAR1 and
ADAR2. This genetic recoding process is known to play essential roles in ... Cited by 3 - Related articles - All 7 versions
