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Scholar Results 1 - 10 of about 36 citing Coward: The human glomerular podocyte is a novel target for insulin action. (0.10 sec) 

Oxidative stress as a major culprit in kidney disease in diabetes

- diabetesjournals.org
JM Forbes, MT Coughlan, ME Cooper - Diabetes, 2008 - Am Diabetes Assoc
It is postulated that localized tissue oxidative stress is a key component in
the development of diabetic nephropathy. There remains controversy, however, as
to whether this is an early link between hyperglycemia and renal disease or ...
Cited by 45 - Related articles - All 3 versions

Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with …


HJ Baelde, M Eikmans, DWP Lappin, PP Doran, … - Kidney international, 2007 - nature.com
Micro-vascular and renal complications in diabetic patients are a considerable
clinical challenge. In a previous study, we found a significant decrease in
vascular endothelial growth factor A (VEGF-A) mRNA levels in glomeruli from ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Nephrin is critical for the action of insulin on human glomerular podocytes


RJM Coward, GI Welsh, A Koziell, S Hussain, … - Diabetes, 2007 - Am Diabetes Assoc
The leading causes of albuminuria and end-stage renal failure are secondary to
abnormalities in the production or cellular action of insulin, including
diabetes and hyperinsulinemic metabolic syndrome. The human glomerular ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Activation of a local renin angiotensin system in podocytes by glucose

- physiology.org [PDF] 
RV Durvasula, SJ Shankland - American Journal of Physiology- Renal Physiology, 2008 - Am Physiological Soc
48 articles, 21 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/294/4/F830#BIBL ... 3 other
HighWire hosted articles: This article has been cited by
Cited by 13 - Related articles - BL Direct - All 3 versions

The podocyte and diabetes mellitus: is the podocyte the key to the origins of diabetic …

- problemsinanes.com
GR Reddy, K Kotlyarevska, RF Ransom, RK … - Current Opinion in Nephrology and Hypertension, 2008 - journals.lww.com
Introduction Diabetes mellitus accounts for approximately one-third of all new
cases of end stage renal disease (ESRD) worldwide, and is the most common cause
of ESRD in the United States where approximately 45% of new cases of ESRD ...
Cited by 13 - Related articles - BL Direct - All 9 versions

Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of …


A Whaley-Connell, VG DeMarco, G Lastra, C … - Am J Nephrol, 2008 - content.karger.com
Background/Aim: There is an emerging relationship between insulin
resistance/hyperinsulinemia, oxidative stress, and glomerular injury manifesting
as albuminuria. HMG-CoA reductase inhibitors (statins) have been shown to ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Obesity and insulin resistance as risk factors for chronic kidney disease


A Whaley-Connell, BS Pavey, A Afroze, GL … - J Cardiometab Syndr, 2006 - interscience.wiley.com
The cardiometabolic syndrome is a state of metabolic and vascular dysregulation.
The cardiometabolic syndrome is clinically composed of a cluster of metabolic
abnormalities including insulin resistancelhyperinsulinemia, ...
Cited by 10 - Related articles

Minimal change nephropathy and focal segmental glomerulosclerosis


PW Mathieson - Seminars in Immunopathology, 2007 - Springer
Abstract The terms minimal change nephropathy and focal segmental
glomerulosclerosis describe histopatholog- ical entities diagnosed by renal
biopsy, typically in patients presenting with heavy proteinuria and its ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Redox control of renal function and hypertension

- nih.gov
R Nistala, A Whaley-Connell, JR Sowers - Antioxidants & redox signaling, 2008 - liebertonline.com
ANTIOXIDANTS & REDOX SIGNALING Volume 10, Number 12, 2008 © Mary Ann Liebert,
Inc. DOI: 10.1089/ars.2008.2034 ... Redox Control of Renal Function and
Hypertension ... Ravi Nistala, 1,3,5 Adam Whaley-Connell, 1,3,5,6 and ...
Cited by 8 - Related articles - All 4 versions

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy …


T Tejada, P Catanuto, A Ijaz, JV Santos, X Xia … - Kidney International, 2008 - nature.com
Loss of podocytes by apoptosis characterizes the early stages of diabetic
nephropathy. To examine its mechanism we studied glomeruli and podocytes
isolated from db/db mice with early diabetic nephropathy and albuminuria. ...
Cited by 7 - Related articles - BL Direct - All 4 versions


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