J Gudmundsson, P Sulem, V Steinthorsdottir, JT … - Nature genetics, 2007 - nature.com We performed a genome-wide association scan to search for sequence variants conferring risk of
prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. Follow-up
studies involving three additional ... Cited by 188 - Related articles - BL Direct - All 17 versions
- ►asnjournals.org T Ulinski, S Lescure, S Beaufils, V Guigonis, S … - Journal of the American …, 2006 - Am Soc Nephrol The hepatocyte nuclear factor-1 encoded by the TCF2 gene plays a role for the specific regulation of
gene expression in various tissues such as liver, kidney, intestine, and pancreatic islets and is
involved in the embryonic ... Cited by 46 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org S Weber, V Moriniere, T Knuppel, M Charbit, J … - Journal of the American …, 2006 - Am Soc Nephrol Renal hypodysplasia (RHD) is characterized by a reduced nephron number, small kidney size, and
disorganized renal tissue. A hereditary basis has been established for a subset of affected
patients, suggesting a major role ... Cited by 46 - Related articles - BL Direct - All 7 versions
AT Hattersley, ER Pearson - Endocrinology, 2006 - Endocrine Soc Defining the molecular genetics of diabetes gives new insight into the underlying etiology and so
should help improve treatment. The genetic etiology is now known for most patients with ß-cell
monogenic diabetes, allowing ... Cited by 43 - Related articles - BL Direct - All 8 versions
KR Owen, MI McCarthy - Current opinion in genetics & development, 2007 - Elsevier Identification and characterization of genetic variants that either cause or predispose to diabetes
are a major focus of biomedical research. As of early 2007, the molecular basis of most forms of
monogenic diabetes resulting from ... Cited by 36 - Related articles - All 4 versions
- ►nih.gov HC Mefford, S Clauin, AJ Sharp, RS Moller, R … - The American Journal of …, 2007 - Elsevier Most studies of genomic disorders have focused on patients with cognitive disability and/or
peripheral nervous system defects. In an effort to broaden the phenotypic spectrum of this disease
model, we assessed 155 autopsy ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►nih.gov MI McCarthy, E Zeggini - Current Diabetes Reports, 2006 - Springer Introduction The growing prevalence of type 2 diabetes and obesity in societies worldwide is widely
recognized as among the greatest threats to global health in the coming century [1]. Nevertheless,
we remain far from a comprehensive ... Cited by 31 - Related articles - BL Direct - All 8 versions
M Vaxillaire, P Froguel - Endocrinology and metabolism clinics of North America, 2006 - Elsevier Type 2 diabetes mellitus (T2D) is a heterogeneous metabolic disease occurring with concomitant or
interdependent defects of insulin secretion and action [1] and [2]. It generally is accepted that
T2D results from a complex ... Cited by 30 - Related articles - All 4 versions
- ►oxfordjournals.org C Haumaitre, M Fabre, S Cormier, C … - Human molecular …, 2006 - Oxford Univ Press Heterozygous mutations in the HNF1ß/vHNF1/TCF2 gene cause maturity-onset diabetes of the young
(MODY5), associated with severe renal disease and abnormal genital tract. Here, we characterize two
fetuses, a 27-week male and a ... Cited by 29 - Related articles - BL Direct - All 6 versions
R Murphy, S Ellard, AT Hattersley - Nature Clinical Practice Endocrinology …, 2008 - nature.com Sian Ellard is Professor of Human Molecular Genetics, Peninsula Medical School, Exeter, UK.
Following research training at the University of Swansea (UK), she set up the Molecular Genetics
Laboratory in Exeter with Professor ... Cited by 31 - Related articles - BL Direct - All 6 versions
