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Scholar Results 1 - 8 of 8 citing Shearer: Partial Gene Deletion of Heart-Type Fatty Acid–Binding Protein Limits the Severity.... (0.10 sec) 

Protection against Western diet-induced obesity and hepatic steatosis in liver fatty …


EP Newberry, Y Xie, SM Kennedy, J Luo, NO … - Hepatology, 2006 - interscience.wiley.com
Liver fatty acid-binding protein (L-Fabp) regulates murine hepatic fatty acid trafficking in response
to fasting. In this study, we show that L-Fabp -/- mice fed a high-fat Western diet for up to 18 weeks
are less obese and accumulate less hepatic triglyceride than C57BL/6J controls. ...
Cited by 49 - Related articles - BL Direct - All 3 versions

Hyperresistinemia is associated with coexistence of hypertension and type 2 …


Y Takata, H Osawa, M Kurata, M Kurokawa, J … - Hypertension, 2008 - Am Heart Assoc
Numerous studies have demonstrated that high blood pressure substantially increases the risk
of microvascular and macrovascular complications in patients with type 2 diabetes mellitus
(T2DM). Currently, we found that serum resistin, an adipocyte- and monocyte-derived ...
Cited by 8 - Related articles - All 6 versions

Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome


E Erbay, H Cao, GS Hotamisligil - Current Atherosclerosis Reports, 2007 - Springer
The link between inflammation and the development of insulin resistance, type 2 diabetes, and
atherosclerosis has been uncovered in the past decade. Although the molecular mechanisms
underlying the co-occurrence of these metabolic and inflammatory diseases are not fully ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Metabolomic profiling of dietary-induced insulin resistance in the high fat-fed …


J Shearer, G Duggan, A Weljie, DS Hittel, DH … - Diabetes Obes …, 2008 - interscience.wiley.com
The predictive ability of metabolic profiling to detect obesity-induced perturbations in metabolism
has not been clearly established. Complex aetiologies interacting with environmental factors
highlight the need to understand how specific manipulations alter metabolite profiles in ...
Cited by 6 - Related articles - All 2 versions

Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: Studies …


PJ Voshol, PCN Rensen, KW van Dijk, JA Romijn, … - BBA-Molecular and Cell …, 2009 - Elsevier
The obesity epidemic is associated with an increased incidence of type 2 diabetes, cardiovascular
morbidity and various types of cancer. A better insight into the molecular mechanisms that underlie
adipogenesis and obesity may result in novel therapeutic handles to fight obesity and ...
Cited by 2 - Related articles - All 2 versions

Energy restriction enhances therapeutic efficacy of the PPARgamma agonist, …


GB Moore, LC Pickavance, CP Briscoe, JC … - Diabetes Obes. …, 2008 - interscience.wiley.com
Aim: Consumption of a palatable diet can induce hyperphagia, leading to weight gain (dietary
obesity) and insulin resistance in rats. Thiazolidinediones (TZDs) can also induce hyperphagia
in rats but conversely have an insulin-sensitizing effect. The aim of this study was to ...
Cited by 1 - Related articles - All 2 versions

Metabolic implications of reduced heart-type fatty acid binding protein in insulin …


J Shearer, PT Fueger, ZZ Wang, DP Bracy, DH … - BBA-Molecular Basis of …, 2008 - Elsevier
Insulin resistance is characterized by elevated rates of cardiac fatty acid utilization resulting in
reduced efficiency and cardiomyopathy. One potential therapeutic approach is to limit the uptake
and oxidation of fatty acids. The aims of this study were to determine whether a ...
Cited by 1 - Related articles - All 3 versions

Induction of fatty acid-binding protein 3 in brown adipose tissue correlates with …


H Yamashita, Z Wang, Y Wang, M Segawa, T … - … and Biophysical Research …, 2008 - Elsevier
We investigated the contribution of fatty acid-binding protein 3 (FABP3) to adaptive thermogenesis
in brown adipose tissue (BAT) in rodents. The expression of FABP3 mRNA in BAT was regulated
discriminatively in response to alteration of the ambient temperature, which regulation ...
Related articles - All 2 versions


 


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