- ►diabetesjournals.org GK Bandyopadhyay, JG Yu, J Ofrecio, JM … - Diabetes, 2006 - Am Diabetes Assoc Increased accumulation of fatty acids and their derivatives can impair
insulin-stimulated glucose disposal by skeletal muscle. To characterize the
nature of the defects in lipid metabolism and to evaluate the effects of ... Cited by 78 - Related articles - BL Direct - All 5 versions
- ►physiology.org CR Bruce, A Thrush, VA Mertz, V Bezaire, A … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Muscle fatty acid (FA) metabolism is impaired in obesity and insulin resistance,
reflected by reduced rates of FA oxidation and accumulation of lipids. It has
been suggested that interventions that increase FA oxidation may enhance ... Cited by 68 - Related articles - BL Direct - All 5 versions
EW Kraegen, GJ Cooney - Current Opinion in Lipidology, 2008 - journals.lww.com Introduction The hypothesis that insulin resistance is related to tri- glyceride
accumulation in muscle and liver dates back to studies of 15–20 years ago
showing that triglyceride accumulates in muscle of high fat-fed rats, ... Cited by 25 - Related articles - BL Direct - All 2 versions
M Lafontan, N Viguerie - Current opinion in pharmacology, 2006 - Elsevier Leptin and adiponectin are the major adipokines secreted by fat cells. Leptin
effects energy homeostasis by decreasing food intake and by acting on
lipogenesis and fatty acid oxidation. Elucidation of the mechanisms of ... Cited by 23 - Related articles - All 2 versions
- ►physiology.org GP Holloway, A Thrush, GJF Heigenhauser, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc A reduction in fatty acid oxidation has been associated with lipid accumulation
and insulin resistance in the skeletal muscle of obese individuals. We examined
whether this decrease in fatty acid oxidation was attributable to a ... Cited by 23 - Related articles - BL Direct - All 7 versions
CE Quinn, PK Hamilton, CJ Lockhart, GE … - British Journal of Pharmacology, 2008 - pubmedcentral.nih.gov Thiazolidinediones (TZDs) have been used for the treatment of hyperglycaemia in
type 2 diabetes for the past 10 years. They may delay the development of type 2
diabetes in individuals at high risk of developing the condition, and have ... Cited by 21 - Related articles - BL Direct - All 4 versions
A Caligiuri, C Bertolani, CT Guerra, S Aleffi, S … - Hepatology, 2008 - interscience.wiley.com Adiponectin limits the development of liver fibrosis and activates adenosine
monophosphate-activated protein kinase (AMPK). AMPK is a sensor of the cellular
energy status, but its possible modulation of the fibrogenic properties of ... Cited by 20 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org JM Ye, N Dzamko, AJ Hoy, MA Iglesias, B … - Diabetes, 2006 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) has been implicated in the
insulin-sensitizing actions of thiazolidinediones (TZDs), but it is not known
whether TZD treatment can enhance tissue glucose uptake in response to AMPK ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►bentham.org [PDF] GR Steinberg, B Jorgensen… - Mini reviews in medicinal chemistry, 2007 - ingentaconnect.com Gregory R. Steinberg * and Sebastian Beck Jørgensen St. Vincent's Institute of
Medical Research and Department of Medicine, University of Melbourne, Melbourne,
Australia Abstract: Over the past decade, an epidemic of obesity has ... Cited by 17 - Related articles - BL Direct - All 6 versions
- ►physiology.org KL Mullen, AC Smith, KA Junkin, DJ Dyck - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc High-fat (HF) diets induce insulin resistance and alter lipid metabolism,
although controversy exists regarding the impact of saturated vs.
polyunsaturated fats. Adiponectin (Ad) stimulates fatty acid (FA) oxidation ... Cited by 12 - Related articles - BL Direct - All 6 versions
