- ►meduni-graz.at [PDF] G Haemmerle, A Lass, R Zimmermann, G Gorkiewicz, … - Science, 2006 - sciencemag.org Fat tissue is the most important energy depot in vertebrates. The release of free fatty acids (FFAs)
from stored fat requires the enzymatic activity of lipases. We showed that genetic inactivation of
adipose triglyceride lipase (ATGL) ... Cited by 170 - Related articles - BL Direct - All 11 versions
- ►jbc.org M Schweiger, R Schreiber, G Haemmerle, A Lass, … - Journal of Biological …, 2006 - ASBMB The mobilization of free fatty acids from adipose triacylglycerol (TG) stores requires the
activities of triacylglycerol lipases. In this study, we demonstrate that adipose triglyceride
lipase (ATGL) and hormone-sensitive ... Cited by 89 - Related articles - All 6 versions
- ►jlr.org DL Brasaemle - The Journal of Lipid Research, 2007 - ASBMB The majority of eukaryotic cells synthesize neutral lipids and package them into cytosolic lipid
droplets. In vertebrates, triacylglycerol-rich lipid droplets of adipocytes provide a major energy
storage depot for the body, whereas ... Cited by 76 - Related articles - All 5 versions
D Langin - Pharmacological research, 2006 - Elsevier Adipose tissue lipolysis is the catabolic process leading to the breakdown of triglycerides stored
in fat cells and release of fatty acids and glycerol. Recent work has revealed that lipolysis is not
a simple metabolic pathway ... Cited by 64 - Related articles - All 5 versions
- ►physiology.org JY Kim, K Tillison, JH Lee, DA Rearick, … - American Journal of …, 2006 - Am Physiological Soc The minimal adipose phenotype of hormone-sensitive lipase (HSL)-null mice suggested that other
hormonally responsive lipase(s) were present in adipocytes. Recent studies have characterized a new
adipose tissue triglyceride lipase, ... Cited by 42 - Related articles - BL Direct - All 4 versions
A Mairal, D Langin, P Arner, J Hoffstedt - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1629–1636 DOI 10.1007/s00125-006-0272-x ARTICLE A. Mairal .
D. Langin . P. Arner . J. Hoffstedt Human adipose triglyceride lipase (PNPLA2) is not regulated
by obesity and exhibits low in vitro triglyceride hydrolase activity ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►physiology.org M Ryden, J Jocken, V van Harmelen, A … - American Journal of …, 2007 - Am Physiological Soc Hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) regulate adipocyte lipolysis
in rodents. The purpose of this study was to compare the roles of these lipases for lipolysis in
human adipocytes. Subcutaneous ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►jlr.org TJ Bartness, CK Song - The Journal of Lipid Research, 2007 - ASBMB During our study of the reversal of seasonal obesity in Siberian hamsters, we found an interaction
between receptors for the pineal hormone melatonin and the sympathetic nervous system (SNS) outflow
from brain to white adipose tissue ... Cited by 31 - Related articles - All 5 versions
- ►cell.com D Langin, P Arner - Trends in Endocrinology & Metabolism, 2006 - Elsevier Catecholamines and natriuretic peptides stimulate human adipocyte lipolysis through an increase in
cAMP and cGMP levels, resulting in phosphorylation and activation of hormone-sensitive lipase. A
defect in hormone-sensitive lipase ... Cited by 30 - Related articles - All 7 versions
- ►endojournals.org JWE Jocken, D Langin, E Smit, WHM Saris, C … - Journal of Clinical …, 2007 - Endocrine Soc Results: Fasting insulin levels and the degree of insulin resistance (using the homeostasis model
assessment index for insulin resistance) were negatively correlated with ATGL and HSL protein
expression, independent of age, ... Cited by 28 - Related articles - BL Direct - All 8 versions
