- ►diabetesjournals.org K Maedler, DM Schumann, N Sauter, H … - Diabetes, 2006 - Am Diabetes Assoc High glucose concentrations have a dual effect on β-cell turnover, inducing
proliferation in the short-term and apoptosis in the long-term. Hyperglycemia
leads to β-cell production of interleuking (IL)-1β in human pancreatic ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►endojournals.org MY Donath, J Storling, LA Berchtold, N … - Endocrine Reviews, 2008 - Endocrine Soc The tale of cytokines and the β-cell is a long story, starting with in vitro
discovery in 1984, evolving via descriptive and phenomenological studies to
detailed mapping of the signalling pathways, gene- and protein expression ... Cited by 20 - Related articles - BL Direct - All 6 versions
K Maedler, DM Schumann, N Sauter, H … - Diabetes, 2006 - Am Diabetes Assoc T he capacity of the pancreatic -cell to adaptively increase insulin secretion
in response to long- term insulin resistance (for example in obesity) is
fundamental to the maintenance of normogly- cemia. Failure of such a ... Cited by 9 - Related articles - All 3 versions
JA Ehses, S Calderari, JC Irminger, P … - Current Immunology Reviews, 2007 - ingentaconnect.com 1 CNRS UMR 7059, Université Paris 7-D Diderot, Paris, France 2 Department of
Internal Medicine, Division of Endocrinology & Diabetes, University Hospital of
Zürich and Center for Integrative Human Physiology, Zürich, Switzerland 3 ... Cited by 4 - Related articles - BL Direct
- ►endojournals.org O Wang, K Cai, S Pang, T Wang, D Qi, Q Zhu, … - Endocrinology, 2008 - Endocrine Soc Pancreatic-derived factor (PANDER) is a cytokine-like peptide highly expressed
in pancreatic β-cells. PANDER was reported to promote apoptosis of pancreatic
β-cells and secrete in response to glucose. Here we explored the effects ... Cited by 4 - Related articles - BL Direct - All 4 versions
H Hua, N Sarvetnick - Endocrine, 2007 - Springer Abstract Inhibitors of DNA binding proteins (Ids) are implicated in the control
of proliferation and differentiation. Herein, we tested the hypothesis that Id2
could stimulate proliferation and survival in differentiated pancreatic ... Cited by 3 - Related articles - BL Direct - All 3 versions
- ►nih.gov BR Burkhardt, JR Cook, RA Young, BA Wolf - BBA-Gene Regulatory Mechanisms, 2008 - Elsevier Pancreatic Derived Factor (PANDER) is a novel cytokine-like protein dominantly
expressed within the endocrine pancreas. Our previous study demonstrated that
the PANDER promoter was both tissue-specific and glucose-responsive. ... Cited by 2 - Related articles - All 3 versions
J Yang, C Wang, J Li, BR Burkhardt, CE … - FEBS letters, 2009 - Elsevier PANDER is a cytokine co-secreted with insulin from islet β-cells. To date, the
physiological function of PANDER remains largely unknown. Here we show that
PANDER binds to the liver membrane by 125 I-PANDER saturation and ... Related articles - All 2 versions
O Wang, K Cai, S Pang, T Wang, D Qi, Q Zhu, … - Citeseer Page 1. 1 Mechanisms of glucose-induced expression of pancreatic-derived
factor in pancreatic β-cells Oumei Wang, Kun Cai, Shanshan ... Related articles - View as HTML