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Scholar Results 1 - 10 of about 26 citing Wijekoon: Homocysteine metabolism in ZDF (type 2) diabetic rats. (0.09 sec) 

H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells

- jbc.org
G Yang, W Yang, L Wu, R Wang - Journal of Biological Chemistry, 2007 - ASBMB
Cystathionine -lyase (CSE) is a key enzyme in the trans-sulfuration pathway,
which uses L-cysteine to produce hydrogen sulfide (H 2 S). Functional changes of
pancreatic beta cells induced by endogenous H 2 S have been reported, but ...
Cited by 32 - Related articles - All 6 versions

Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in …

- physiology.org
S Ratnam, EP Wijekoon, B Hall, TA Garrow, … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Elevation of plasma homocysteine levels has been recognized as an independent
risk factor for the development of cardiovascular disease, a major complication
of diabetes. Plasma homocysteine reflects a balance between its synthesis ...
Cited by 19 - Related articles - BL Direct - All 3 versions

New insights into the regulation of methyl group and homocysteine metabolism

- nutrition.org
KT Williams, KL Schalinske - Journal of Nutrition, 2007 - Am Soc Nutrition
Hepatic folate, methyl group, and homocysteine metabolism are interrelated
pathways that when disrupted are associated with numerous pathologies.
Maintenance of normal methyl group and homocysteine homeostasis is ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

- csic.es [PDF] 
MA Pajares, D Perez-Sala - Cellular and molecular life sciences, 2006 - Springer
In recent years, homocysteine (Hcy) has become a sub- ject of great interest,
due to its implication as a risk factor for cardiovascular diseases. However,
increases in plasma levels (tHcy) have also been detected in disorders such ...
Cited by 12 - Related articles - BL Direct - All 7 versions

Extra virgin olive oils increase hepatic fat accumulation and hepatic antioxidant protein …

- ciberobn.info [PDF] 
JM Arbones-Mainar, K Ross, GJ Rucklidge, M … - J. Proteome Res, 2007 - pubs.acs.org
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... Division of Vascular Health, Rowett Research Institute.
Cited by 11 - Related articles - All 6 versions

Overexpression of angiopoietin-like protein 4 alters mitochondria activities and modulates …

- endojournals.org
Y Wang, KSL Lam, JBB Lam, MC Lam, PTY … - Molecular Endocrinology, 2007 - Endocrine Soc
Angiopoietin-like protein 4 (ANGPTL4) is a circulating protein predominantly
produced from fat tissue and liver. Recent data from others and our laboratory
have demonstrated this protein to be an important player in energy ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic …

- nutrition.org
CS Hartz, KM Nieman, RL Jacobs, DE Vance, … - Journal of Nutrition, 2006 - Am Soc Nutrition
Phosphatidylcholine is an essential phospholipid that is synthesized by 2
different pathways, the CDP-choline pathway and the methylation of
phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome

- oxfordjournals.org
X Ma, L Fan, Y Meng, Z Hou, YD Mao, W Wang … - Molecular human reproduction, 2007 - Oxford Univ Press
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory
infertility, affecting 5–10% of females of reproductive age. Currently, little
is known about the changes in whole proteins between PCOS and normal ...
Cited by 9 - Related articles - BL Direct - All 7 versions

Folate status modulates the induction of hepatic glycine N-methyltransferase and …

- physiology.org
KM Nieman, CS Hartz, SS Szegedi, TA Garrow … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
A diabetic state induces the activity and abundance of glycine
N-methyltransferase (GNMT), a key protein in the regulation of folate, methyl
group, and homocysteine metabolism. Because the folate-dependent one-carbon ...
Cited by 8 - Related articles - BL Direct - All 4 versions

[PDF] Homocysteine metabolism in diabetes


EP Wijekoon, ME Brosnan, JT Brosnan - Biochemical Society Transactions, 2007 - biochemsoctrans.cn
Abstract An increase in the plasma level of Hcy (homocysteine), an intermediate
in the catabolism of methionine, has been identified as a risk factor for many
diseases including CVD (cardiovascular disease). CVD is the major cause of ...
Cited by 9 - Related articles - View as HTML - BL Direct - All 4 versions


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