JM Chen, C Ferec, DN Cooper - Human genetics, 2006 - Springer Abstract In an attempt both to catalogue 3¢ regulatory region (3¢ RR)-mediated
disease and to improve our understanding of the structure and function of the
3¢ RR, we have performed a systematic analysis of disease- associated ... Cited by 29 - Related articles - BL Direct - All 4 versions
N Abate, M Chandalia, R Di Paola, DW Foster, … - Nature Reviews Endocrinology, 2006 - nature.com Insulin resistance is pathogenic for type 2 diabetes and cardiovascular disease.
Several inhibitors of insulin signaling have a role in human insulin resistance.
The transmembrane glycoprotein ectonucleotide pyrophosphatase ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►ciberobn.es [PDF] J López-Miranda, P Pérez-Martínez, C Marin, … - Journal of Molecular Medicine, 2007 - Springer Abstract Both insulin resistance and dyslipidaemia are determined by genetic and
environmental factors. Depending on their expression and their function, gene
variants may influence either insulin action or dyslipidaemia. The purpose ... Cited by 4 - Related articles - BL Direct - All 6 versions
M Traurig, RL Hanson, S Kobes, C Bogardus, … - Diabetologia, 2007 - Springer Abstract Aim/hypothesis Single-nucleotide polymorphisms (SNPs) in the protein
tyrosine phosphatase 1B gene (PTPN1) have been reported to be associated with
type 2 diabetes in white subjects, and insulin sensitivity and fasting ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►twin-research.ac.uk [PDF] H Snieder, X Wang, R Shiri-Sverdlov, JV van … - Diabetologia, 2008 - Springer Abstract Aims/hypotheses We recently reported significant associa- tions between
BMI and three TUB single nucleotide polymorphisms (SNPs) in two Dutch cohorts
enriched for type 2 diabetes. Here, we attempted a replication of these ... Cited by 2 - Related articles - BL Direct - All 8 versions
R Meshkani, M Taghikhani, A Mosapour, B … - Archives of medical research, 2007 - Elsevier Protein tyrosine phosphatase 1B (PTP1B), encoded by the PTPN1 gene, efficiently
dephosphorylates the insulin receptor, and attenuates insulin signaling.
Recently, a 1484insG variant of the PTPN1 gene has been associated with an ... Cited by 1 - Related articles - All 6 versions
AJ Nichols, RD Mashal, B Balkan - Drug Development Research, 2006 - interscience.wiley.com PTP1B is a protein tyrosine phosphatase involved in insulin and leptin signaling
and is a primary mechanism for down-regulating both the insulin and leptin
receptor signaling pathways. Animals deficient in PTP1B have improved ... Cited by 1 - Related articles - BL Direct - All 2 versions
A Raji, JS Williams, PN Hopkins, DC … - Journal of Clinical Hypertension, 2006 - interscience.wiley.com The authors assessed the familial aggregation of cardiometabolic abnormalities
(elevated homeostasis model assessment [HOMA], triglycerides [TG], and
low-density lipoprotein [LDL] and reduced high-density lipoprotein [HDL]) ... Cited by 1 - Related articles - BL Direct - All 3 versions
