Q Tang, JA Bluestone - Immunological reviews, 2006 - interscience.wiley.com Summary: Endowed with the ability to actively suppress an immune response,
regulatory T cells (Tregs) hold the promise of halting ongoing pathogenic
autoimmunity and restoring self-tolerance in patients suffering from ... Cited by 116 - Related articles - BL Direct - All 5 versions
K Mahnke, TS Johnson, S Ring, AH Enk - Journal of Dermatological Science, 2007 - Elsevier At first glance, dendritic cells (DCs) and regulatory T cells (Tregs) do not
have much in common. DCs are characterized by their unsurpassed T cell
stimulatory capacity, whereas Tregs are marked by the ability to suppress ... Cited by 47 - Related articles - All 8 versions
K Kretschmer, I Apostolou, E Jaeckel, K … - Immunological reviews, 2006 - interscience.wiley.com Summary: There is increasing evidence that agonist ligand presentation either
intrathymically or extrathymically plays a crucial if not essential role in the
generation of regulatory T cells (Tregs). Thus, it is possible to induce ... Cited by 44 - Related articles - BL Direct - All 4 versions
E Suri-Payer, B Fritzsching - Springer seminars in immunopathology, 2006 - Springer Page 1. REVIEW Regulatory T cells in experimental autoimmune disease Elisabeth
Suri-Payer & Benedikt Fritzsching Received: 23 March ... Cited by 34 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org W Hansen, K Loser, AM Westendorf, D Bruder, … - The Journal of Immunology, 2006 - Am Assoc Immnol Foxp3 functions as a lineage specification factor for the development of
naturally occurring thymus-derived CD4 + CD25 + regulatory T (Treg) cells.
Recent evidence suggests that naive Foxp3 – CD4 + CD25 – T cells can be ... Cited by 23 - Related articles - BL Direct - All 6 versions
K Mahnke, T Bedke, AH Enk - Cellular Immunology, 2007 - Elsevier Regulatory T cells (Treg) were originally described by their suppressive
function exerted on effector T cells, but recent evidence also reveals
interactions with antigen presenting cells (APCs). In general, all major ... Cited by 19 - Related articles - All 2 versions
- ►nih.gov CB Stober, S Brode, JK White, JF Popoff, JM … - Infection and Immunity, 2007 - iai.highwire.org Solute carrier family 11 member a1 (Slc11a1; formerly Nramp1) encodes a late
endosomal/lysosomal protein/divalent cation transporter that regulates iron
homeostasis in macrophages. During macrophage activation, Slc11a1 has ... Cited by 12 - Related articles - BL Direct - All 6 versions
- ►nih.gov A Mukhopadhaya, T Hanafusa, I Jarchum, YG … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Type 1 diabetes (T1D) is an autoimmune disease resulting from defects in central
and peripheral tolerance and characterized by T cell-mediated destruction of
islet β cells. Cytotoxic CD8 + T cells, reactive to β cell antigens, are ... Cited by 8 - Related articles - BL Direct - All 7 versions
AL Cava, FD Shi - Current medicinal chemistry, 2006 - ingentaconnect.com Abstract: Recent studies have raised great interest in the modulation of
autoimmune responses by manipulation of immunoregulatory cells. Several
lymphocyte subpopulations responsible for the induction and maintenance of ... Cited by 8 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org W Hansen, AM Westendorf, S Reinwald, D … - The Journal of Immunology, 2007 - Am Assoc Immnol The concept of immune regulation/suppression has been well-established and,
besides thymus-derived CD4 + CD25 + regulatory T (T R ) cells, it became clear
that a variety of additional peripherally induced T R cells play vital ... Cited by 6 - Related articles - All 2 versions
