- ►nih.gov P Pacher, C Szabó - Current opinion in pharmacology, 2006 - Elsevier Hyperglycemic episodes, which complicate even well-controlled cases of diabetes,
lead to increased polyol pathway flux, activation of protein kinase C and
accelerated non-enzymatic formation of advanced glycation end products. ... Cited by 43 - Related articles - All 5 versions
- ►diabetesjournals.org C Szabó, A Biser, R Benkő, E Böttinger, K … - Diabetes, 2006 - Am Diabetes Assoc The activation of the poly(ADP-ribose) polymerase (PARP) plays an important role
in the pathophysiology of various diseases associated with oxidative stress. We
found increased amounts of poly(ADP) ribosylated proteins in diabetic ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►nih.gov O Ilnytska, VV Lyzogubov, MJ Stevens, VR … - Diabetes, 2006 - Am Diabetes Assoc Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental
mechanism in the pathogenesis of diabetes complications including diabetic
neuropathy. This study evaluated the role of PARP in diabetic sensory ... Cited by 26 - Related articles - BL Direct - All 10 versions
PJ Oates - Current drug targets, 2008 - ingentaconnect.com Abstract: Aldose reductase (AR) enzymatically transforms cytosolic glucose into
sorbitol, a molecule that poorly pene- trates cell membranes and is sometimes
slowly metabolized. Hyperglycemia can cause intracellular accumulation of ... Cited by 26 - Related articles - BL Direct - All 3 versions
CA de la Lastra, I Villegas, S Sanchez-Fidalgo - Current pharmaceutical design, 2007 - ingentaconnect.com Abstract: Poly(ADP-ribose) polymerase (PARP) comprise of a family of enzymes
which catalyses poly(ADP- ribosyl)ation of DNA-binding proteins. To date, seven
isoforms have been identified: PARP-1, PARP-2, PARP-3, PARP- 4 ... Cited by 25 - Related articles - BL Direct - All 3 versions
- ►shouxi.net IG Obrosova, O Ilnytska, VV Lyzogubov, IA … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—HFD-fed mice developed obesity, increased plasma FFA and insulin
concentrations, and impaired glucose tolerance. They also had motor and sensory
nerve conduction deficits, tactile allodynia, and thermal hypoalgesia in ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►academia.edu [PDF] I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, … - Experimental Neurology, 2007 - Elsevier Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia,
and impaired nitrergic innervation in animal models of Type 1 diabetes. The role
for reactive nitrogen species in Type 2 diabetes-associated neuropathy ... Cited by 19 - Related articles - All 5 versions
DW Zochodne - Muscle and Nerve, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 15 - Related articles - BL Direct - All 4 versions
WT Cefalu - ILAR JOURNAL, 2006 - dels.nas.edu The prevalence of diabetes throughout the world has in- creased dramatically
over the recent past, and the trend will continue for the foreseeable future.
One of the major con- cerns associated with diabetes relates to the ... Cited by 14 - Related articles - View as HTML - BL Direct - All 3 versions
