- ►nih.gov YC Long, JR Zierath - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular
metabolism. When activated by a deficit in nutrient status, AMPK stimulates glucose uptake and
lipid oxidation to produce energy, while turning off energy-consuming processes ... Cited by 166 - Related articles - BL Direct - All 9 versions
AL Carey, GR Steinberg, SL Macaulay, WG Thomas, … - Diabetes, 2006 - Am Diabetes Assoc Although interleukin-6 (IL-6) has been associated with insulin resistance, little is known regarding
the effects of IL-6 on insulin sensitivity in humans in vivo. Here, we show that IL-6 infusion increases
glucose disposal without affecting the complete suppression of endogenous glucose ... Cited by 99 - Related articles - BL Direct - All 6 versions
C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L … - Nature, 2009 - basicmed.med.ncku.edu.tw AMP-activated protein kinase (AMPK) is a metabolic fuel gauge conserved along the evolutionary
scale in eukaryotes that senses changes in the intracellular AMP/ATP ratio1. Recent evidence
indi- cated an important role for AMPK in the therapeutic benefits of metformin2,3, ... Cited by 29 - Related articles - View as HTML - All 9 versions
- ►physiology.org J Li, DL Coven, EJ Miller, X Hu, ME Young … - American Journal of …, 2006 - Am Physiological Soc AMP-activated protein kinase (AMPK) plays a key role in modulating cellular metabolic
processes. AMPK, a serine-threonine kinase, is a heterotrimeric complex of catalytic -subunits
and regulatory - and -subunits with multiple isoforms. Mutations in the cardiac 2 -isoform ... Cited by 20 - Related articles - BL Direct - All 6 versions
YC Long, S Glund, PM Garcia-Roves, JR Zierath - Journal of Biological …, 2007 - ASBMB The metabolic property of skeletal muscle adapts in response to an increased physiological demand
by altering substrate utilization and gene expression. The calcium-regulated serine/threonine
protein phosphatase calcineurin has been implicated in the transduction of motor neuron ... Cited by 17 - Related articles - All 6 versions
- ►physiology.org L Barre, C Richardson, MF Hirshman, J … - American Journal of …, 2007 - Am Physiological Soc The AMP-activated protein kinase (AMPK) is an important metabolic sensor/effector that coordinates
many of the changes in mammalian tissues during variations in energy availability. We have
sought to create an in vivo genetic model of chronic AMPK activation, selecting murine ... Cited by 15 - Related articles - BL Direct - All 5 versions
EC Nilsson, YC Long, S Martinsson, S Glund, P … - Journal of Biological …, 2006 - ASBMB AMP-activated protein kinase (AMPK) is an evolutionarily conserved heterotrimer important for
metabolic sensing in all eukaryotes. The muscle-specific isoform of the regulatory γ-subunit of
the kinase, AMPK γ3, has an important role in glucose uptake, glycogen synthesis, and fat ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►physiology.org JS Ju, MA Gitcho, CA Casmaer, PB Patil, … - American Journal of …, 2007 - Am Physiological Soc Data from the use of activators and inhibitors of the AMP-activated protein kinase (AMPK) suggest
that AMPK increases sensitivity of glucose transport to stimulation by insulin in muscle cells.
We assayed insulin action after adenoviral (Ad) transduction of constitutively active (CA; a ... Cited by 10 - Related articles - BL Direct - All 5 versions
SR Costford, N Kavaslar, N Ahituv, SN Chaudhry, … - PLoS One, 2007 - pubmedcentral.nih.gov AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme that is evolutionarily conserved
from yeast to mammals and functions to maintain cellular and whole body energy
homeostasis. Studies in experimental animals demonstrate that activation of AMPK in ... Cited by 10 - Related articles - All 7 versions
P Weyrich, F Machicao, H Staiger, P Simon, C Thamer, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Role of AMP-activated protein kinase gamma 3 genetic variability in
glucose and lipid metabolism in non- diabetic whites P. Weyrich & F. Machicao & H. Staiger
& P. Simon & C. Thamer & J. Machann & F. Schick & A. Guirguis & ... Cited by 8 - Related articles - BL Direct - All 3 versions
