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Scholar Results 1 - 10 of about 30 citing Somm: Decreased Fat Mass in Interleukin-1 Receptor Antagonist–Deficient Mice. (0.08 sec) 

Adipose tissue-derived factors: impact on health and disease

- endojournals.org
ME Trujillo, PE Scherer - Endocrine reviews, 2006 - Endocrine Soc
The endocrine functions of the adipose organ are widely studied at this stage. The adipose
organ, and in particular adipocytes, communicate with almost all other organs. Although some
adipose tissue pads assume the functions as distinct "miniorgans," adipocytes can also ...
Cited by 119 - Related articles - BL Direct - All 9 versions

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the …


M Poggi, D Bastelica, P Gual, MA Iglesias, T Gremeaux … - Diabetologia, 2007 - Springer
Page 1. ARTICLE C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected
against the development of insulin resistance in white adipose tissue in response to
a high-fat diet M. Poggi & D. Bastelica & P. Gual & MA Iglesias & ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Local adipose tissue depots as cardiovascular risk factors

- cardiovascres.org
S Thalmann, CA Meier - Cardiovascular Research, 2007 - cardiovascres.org
White adipose tissue (WAT) is a highly active organ secreting various peptides such as
cytokines, chemokines and hormone-like proteins. Besides the visceral and subcutaneous
depots, WAT is also found in the close vicinity of blood vessels (perivascular adipose ...
Cited by 22 - Related articles - All 6 versions

Cytokines and {beta}-Cell Biology: from Concept to Clinical Translation

- endojournals.org
MY Donath, J Storling, LA Berchtold, N Billestrup, T … - Endocrine …, 2008 - Endocrine Soc
The tale of cytokines and the β-cell is a long story, starting with in vitro discovery in 1984, evolving
via descriptive and phenomenological studies to detailed mapping of the signalling
pathways, gene- and protein expression patterns, molecular and biochemical effector ...
Cited by 21 - Related articles - BL Direct - All 6 versions

IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?


S Perrier, F Darakhshan, E Hajduch - FEBS letters, 2006 - Elsevier
Many pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and IL-6 are secreted
by adipocytes and have attracted considerable attention as mediators or coordinators of the insulin
resistance observed in inflammatory diseases and obesity (for reviews see [1] and [2]). ...
Cited by 19 - Related articles - All 6 versions

Interleukin-18 controls energy homeostasis by suppressing appetite and feed …

- pnas.org
EP Zorrilla, M Sanchez-Alavez, S … - Proceedings of the …, 2007 - National Acad Sciences
Circulating levels of the cytokine interleukin 18 (IL-18) are elevated in obesity. Here, we show
that administration of IL-18 suppresses appetite, feed efficiency, and weight regain in food-deprived
male and female C57BL/6J mice. Intraperitoneal vs. intracerebroventricular routes of ...
Cited by 17 - Related articles - BL Direct - All 8 versions

Common genetic variation in the gene encoding interleukin-1-receptor antagonist ( …


S Rafiq, K Stevens, AJ Hurst, A Murray, W Henley, … - Genes and immunity, 2007 - nature.com
Interleukin-1-receptor antagonist (IL-1RA) modulates the biological activity of the proinflammatory
cytokine interleukin-1 (IL-1) and could play an important role in the pathophysiology of inflammatory
and metabolic traits. We genotyped seven single nucleotide polymorphisms (SNPs) that ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Effects of chronic exercise on cytokine production in white adipose tissue and …


D Gomez-Merino, C Drogou, CY Guezennec, M … - Cytokine, 2007 - Elsevier
White adipose tissue (WAT) is a major source of production of cytokines involved in chronic diseases
such as obesity, type 2 diabetes, and atherosclerosis. Long-term exercise has been proposed
as a therapy to reduce chronic inflammation. We investigated here the influence of an ...
Cited by 10 - Related articles - All 3 versions

Differential role and tissue specificity of interleukin-1α gene expression in …


Y Kamari, R Werman-Venkert, A Shaish, A Werman, A … - Atherosclerosis, 2007 - Elsevier
We first studied the effect of atherogenic diet on wild-type C57BL/6 IL-1α or IL-1β deficient
mice. IL-1α KO resulted in a comparatively higher total cholesterol levels, compared to WT and
IL-1β KO mice (398 ± 10; 266 ± 19; 223 ± 13 mg/dl, respectively, p < 0.001), due to higher ...
Cited by 8 - Related articles - All 30 versions

Leptin induces interleukin-1beta release from rat microglial cells through a …


E Pinteaux, W Inoue, L Schmidt, F Molina-Holgado … - J …, 2007 - interscience.wiley.com
Leptin regulates energy balance by suppressing appetite and increasing energy expenditure
through actions in the hypothalamus. Recently we demonstrated that the effects of leptin are,
at least in part, mediated by the release of interleukin (IL)-1β in the brain. Microglia ...
Cited by 9 - Related articles - BL Direct - All 5 versions


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