S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that globally the number
of adults affected with diabetes will increase from 135 million in 1995 to 300 million by 2025.
1 Patients with diabetes mellitus are at increased risk for cardiovascular diseases. Thus, ... Cited by 140 - Related articles - All 5 versions
- ►physiology.org S Boudina, ED Abel - Physiology, 2006 - Am Physiological Soc Diabetes is a worldwide epidemic (112). Cardiovascular disease remains the major cause of
morbidity and mortality in people with diabetes. Epidemiological studies suggest that the prevalence
of heart failure exceeds that which can be accounted for by other risk factors such as ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org W Hsueh, ED Abel, JL Breslow, N Maeda, RC … - Circulation …, 2007 - Am Heart Assoc From the Division of Endocrinology, Diabetes, and Hypertension (WH), and Department of
Medicine, Division of Cardiology (RCD), The David Geffen School of Medicine, University of
California, Los Angeles; Division of Endocrinology, Metabolism, and Diabetes (EDA and ... Cited by 39 - Related articles - All 6 versions
- ►endojournals.org GM Sutton, JL Trevaskis, MW Hulver, RP McMillan, NJ … - Endocrinology, 2006 - Endocrine Soc Loss of brain melanocortin receptors (Mc3rKO and Mc4rKO) causes increased adiposity and
exacerbates diet-induced obesity (DIO). Little is known about how Mc3r or Mc4r genotype,
diet, and obesity affect insulin sensitivity. Insulin resistance, assessed by insulin and ... Cited by 29 - Related articles - BL Direct - All 6 versions
ED Abel, SE Litwin, G Sweeney - Physiological Reviews, 2008 - Am Physiological Soc The dramatic increase in the prevalence of obesity and its strong association with cardiovascular
disease have resulted in unprecedented interest in understanding the effects of obesity on the
cardiovascular system. A consistent, but puzzling clinical observation is that obesity ... Cited by 25 - Related articles - BL Direct - All 3 versions
EW Kraegen, GJ Cooney - Current Opinion in Lipidology, 2008 - journals.lww.com Introduction The hypothesis that insulin resistance is related to tri- glyceride accumulation in
muscle and liver dates back to studies of 15–20 years ago showing that triglyceride accumulates
in muscle of high fat-fed rats, coincident with insulin resistance [1,2]. Since then the ... Cited by 25 - Related articles - BL Direct - All 2 versions
- ►physiology.org GD Thakker, NG Frangogiannis, M Bujak, … - American Journal of …, 2006 - Am Physiological Soc Epidemiological studies indicate that obesity, insulin resistance, and diabetes are important comorbidities
of patients with ischemic heart disease and increase mortality and development of congestive
heart failure after myocardial infarction. Although ob/ob and db/db mice are commonly ... Cited by 24 - Related articles - BL Direct - All 6 versions
- ►elsa.org.br [PDF] MI Schmidt, BB Duncan, A Vigo, JS Pankow, D Couper, … - Diabetologia, 2006 - Springer Page 1. ARTICLE Leptin and incident type 2 diabetes: risk or protection? MI Schmidt
& BB Duncan & A. Vigo & JS Pankow & D. Couper & CM Ballantyne & RC
Hoogeveen & G. Heiss · For the ARIC Investigators Received: 7 ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►physiology.org S Lee, R Muniyappa, X Yan, H Chen, LQ … - American Journal of …, 2008 - Am Physiological Soc Insulin resistance contributes to the pathophysiology of diabetes, obesity, and their cardiovascular
complications. Mouse models of these human diseases are useful for gaining insight into pathophysiological
mechanisms. The reference standard for measuring insulin sensitivity in both humans ... Cited by 17 - Related articles - BL Direct - All 3 versions
CR Wilson, MK Tran, KL Salazar, ME … - The Biochemical …, 2007 - pubmedcentral.nih.gov Obesity and diabetes are associated with increased fatty acid availability in excess of muscle
fatty acid oxidation capacity. This mismatch is implicated in the pathogenesis of cardiac contractile
dysfunction and also in the development of skeletal-muscle insulin resistance. We tested ... Cited by 15 - Related articles - BL Direct - All 7 versions
