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Scholar Results 1 - 10 of about 18 citing Qi: HFE genetic variability, body iron stores, and the risk of type 2 diabetes in US women. (0.10 sec) 

Hemochromatosis genotypes and risk of 31 disease endpoints: Meta-analyses …


C Ellervik, H Birgens, A Tybjærg-Hansen, BG … - Hepatology, 2007 - interscience.wiley.com
Hemochromatosis genotypes have been associated with liver disease, diabetes mellitus, heart
disease, arthritis, porphyria cutanea tarda, stroke, neurodegenerative disorders, cancer, and
venous disease. We performed meta-analyses including 202 studies with 66,263 cases ...
Cited by 18 - Related articles - BL Direct - All 2 versions

The common obesity variant near MC4R gene is associated with higher intakes of …

- oxfordjournals.org
L Qi, P Kraft, DJ Hunter, FB Hu - Human Molecular Genetics, 2008 - Oxford Univ Press
Melanocortin-4 receptor (MC4R) plays critical roles in regulating food intake and energy
balance. Recent genome wide scans found common variants near MC4R were related to obesity
and insulin resistance. We examined the associations of the reported variants ...
Cited by 16 - Related articles - All 4 versions

Heme iron from diet as a risk factor for coronary heart disease in women with type 2 …


L Qi, RM van Dam, K Rexrode, FB Hu - Diabetes care, 2007 - Am Diabetes Assoc
RESULTS—During 54,455 person-years of follow-up from 1980 through 2000, we documented
550 incident cases of CHD. After adjustment for age and BMI, high intakes of both heme iron
and red meat were associated with a significantly increased risk of fatal CHD (P for trend ...
Cited by 11 - Related articles - BL Direct - All 6 versions

Fat Mass–and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity


L Qi, K Kang, C Zhang, RM van Dam, P Kraft, D Hunter, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We observed a trend toward decreasing associations between rs9939609 and BMI
at older age (≥65 years) in men, whereas the associations were constant across different age
groups in women. In addition, the single nucleotide polymorphism (SNP) rs9939609 was ...
Cited by 12 - Related articles - All 3 versions

The role of iron in type 2 diabetes in humans


SN Rajpathak, JP Crandall, J Wylie-Rosett, GC Kabat, … - BBA-General Subjects, 2009 - Elsevier
The role of micronutrients in the etiology of type 2 diabetes is not well established. Several lines
of evidence suggest that iron play may a role in the pathogenesis of type 2 diabetes. Iron is a
strong pro-oxidant and high body iron levels are associated with increased level of ...
Cited by 9 - Related articles - All 2 versions

Interleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 …


L Qi, N Rifai, FB Hu - Diabetes, 2007 - Am Diabetes Assoc
RESULTS— In both control and diabetic patients, polymorphisms within an LD block spanning
∼42 kb were significantly associated with plasma IL-6 levels. A missense variant SNP7 in exon
9 (rs8192284, Asp358Ala) showed the strongest association (P = 0.0005 in control and P ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Variations in Adiponectin Receptor Genes and Susceptibility to Type 2 Diabetes in …

- shouxi.net
L Qi, A Doria, E Giorgi, FB Hu - Diabetes, 2007 - Am Diabetes Assoc
Adiponectin has been associated with low diabetes risk. The metabolic effects of adiponectin
are mediated by adiponectin receptors 1 (ADIPOR1) and 2 (ADIPOR2). We conducted a
prospective, nested case-control study of 714 cases of type 2 diabetes and 1,120 control ...
Cited by 5 - Related articles - BL Direct - All 5 versions

The iron-heart hypothesis: search for the ironclad evidence


FB Hu - Jama, 2007 - Am Med Assoc
The iron-heart hypothesis first put forth by Sullivan 1 in 1981 suggests that increased body iron
stores are a risk factor for coronary heart disease (CHD) and thus that iron depletion through
phlebotomy or other means can reduce risk. The hypothesis, which was based on ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 …


L Qi, RM van Dam, FW Asselbergs, FB Hu - Diabetic Medicine, 2007 - interscience.wiley.com
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Cited by 5 - Related articles - BL Direct - All 3 versions

[PDF] FTO gene variant is associated with obesity: longitudinal analyses in two cohort …


L Qi, K Kang, C Zhang, RM van Dam, P Kraft, D Hunter, … - Diabetes, 2008 - Am Diabetes Assoc
Affiliations: 1: Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts
2: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard
Medical School, Boston, Massachusetts 3: Department of Epidemiology, Harvard School ...
Cited by 1


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