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Scholar Results 1 - 10 of about 53 citing Micallef: Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells. (0.11 sec) 

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

- uni-karlsruhe.de [PDF] 
G Keller - Genes & development, 2005 - genesdev.cshlp.org
The discovery of mouse embryonic stem (ES) cells >20 years ago represented a
major advance in biology and experimental medicine, as it enabled the routine
manipulation of the mouse genome. Along with the capacity to induce genetic ...
Cited by 373 - Related articles - BL Direct - All 12 versions

Inducing embryonic stem cells to differentiate into pancreatic {beta} cells by a novel three- …

- alphamedpress.org
Y Shi, L Hou, F Tang, W Jiang, P Wang, M … - Stem Cells, 2005 - AlphaMed Press
Experimental induction of embryonic stem cells (ESCs) to become pancreatic ß
cells can potentially provide ample resource for cell transplantation therapy of
type I diabetes mellitus. Most of the previously reported induction ...
Cited by 94 - Related articles - All 6 versions

Pancreas and beta-cell development: from the actual to the possible

- biologists.org
LC Murtaugh - Development, 2007 - dev.biologists.org
The development of insulin-producing pancreatic beta (ß)-cells represents the
culmination of a complex developmental program. Cells of the posterior foregut
assume a pancreatic identity, cells within the expanding pancreatic ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Directed differentiation of human embryonic stem cells towards a pancreatic cell fate


JH Shim, SE Kim, DH Woo, SK Kim, CH Oh, R … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Directed differentiation of human embryonic stem cells towards
a pancreatic cell fate JH Shim & SE Kim & DH Woo & SK Kim & ...
Cited by 47 - Related articles - BL Direct - All 5 versions

In vitro derivation of functional insulin-producing cells from human embryonic stem cells


W Jiang, Y Shi, D Zhao, S Chen, J Yong, J … - Cell Research, 2007 - nature.com
The capacity for self-renewal and differentiation of human embryonic stem (ES)
cells makes them a potential source for generation of pancreatic beta cells for
treating type I diabetes mellitus. Here, we report a newly developed and ...
Cited by 44 - Related articles - BL Direct - All 7 versions

Germ layer induction from embryonic stem cells

- ucla.edu [PDF] 
P Gadue, TL Huber, MC Nostro, S Kattman, … - Experimental hematology, 2005 - Elsevier
Embryonic stem (ES) cells have the potential to develop into all cell types of
the adult body. This capability provides the basis for considering the ES cell
system as a novel and unlimited source of cells for replacement therapies ...
Cited by 27 - Related articles - All 12 versions

[PDF] Insulin-producing cells derived from stem cells: recent progress and future directions


A Santana, R Ensenat-Waser, MI Arribas, JA … - Journal of Cellular and Molecular Medicine, 2006 - curemosladiabetes.com
Type 1 diabetes is characterized by the selective destruction of pancreatic
ß-cells caused by an autoimmune attack. Type 2 diabetes is a more complex
pathology which, in addition to ß-cell loss caused by apoptotic programs, ...
Cited by 25 - Related articles - View as HTML - BL Direct - All 5 versions

Differentiation of mouse embryonic stem cells to insulin-producing cells


IS Schroeder, A Rolletschek, P Blyszczuk, G … - Nature Protocols, 2006 - nature.com
Here, we describe a basic protocol for the in vitro differentiation of mouse
embryonic stem (ES) cells into insulin-producing cells. The three-step protocol
comprises (i) the formation of embryoid bodies, (ii) the spontaneous ...
Cited by 20 - Related articles - BL Direct - All 3 versions

Transplantation of 3D scaffolds seeded with human embryonic stem cells: biological features …


JG Lees, SA Lim, T Croll, G Williams, S Lui, … - Regenerative Med., 2007 - Future Medicine
Figure 1.3D cell culturing and transplantation procedure. ... (A) Alkaline
phosphatase staining of hESC colonies. (B)Stage-specific embryonic antigen-4
immunostaining of hESC colony. (C–D) Scanning electron microscopy (SEM) ...
Cited by 17 - Related articles - BL Direct - All 4 versions

Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific …

- alphamedpress.org
N Shiraki, T Yoshida, K Araki, A Umezawa, Y … - Stem Cells, 2008 - AlphaMed Press
The generation of specific lineages of the definitive endoderm from embryonic
stem (ES) cells is an important issue in developmental biology, as well as in
regenerative medicine. This study demonstrates that ES cells are induced ...
Cited by 15 - Related articles - BL Direct - All 6 versions


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