- ►uni-karlsruhe.de [PDF] G Keller - Genes & development, 2005 - genesdev.cshlp.org The discovery of mouse embryonic stem (ES) cells >20 years ago represented a
major advance in biology and experimental medicine, as it enabled the routine
manipulation of the mouse genome. Along with the capacity to induce genetic ... Cited by 373 - Related articles - BL Direct - All 12 versions
- ►alphamedpress.org Y Shi, L Hou, F Tang, W Jiang, P Wang, M … - Stem Cells, 2005 - AlphaMed Press Experimental induction of embryonic stem cells (ESCs) to become pancreatic ß
cells can potentially provide ample resource for cell transplantation therapy of
type I diabetes mellitus. Most of the previously reported induction ... Cited by 94 - Related articles - All 6 versions
- ►biologists.org LC Murtaugh - Development, 2007 - dev.biologists.org The development of insulin-producing pancreatic beta (ß)-cells represents the
culmination of a complex developmental program. Cells of the posterior foregut
assume a pancreatic identity, cells within the expanding pancreatic ... Cited by 54 - Related articles - BL Direct - All 5 versions
JH Shim, SE Kim, DH Woo, SK Kim, CH Oh, R … - Diabetologia, 2007 - Springer Page 1. ARTICLE Directed differentiation of human embryonic stem cells towards
a pancreatic cell fate JH Shim & SE Kim & DH Woo & SK Kim & ... Cited by 47 - Related articles - BL Direct - All 5 versions
W Jiang, Y Shi, D Zhao, S Chen, J Yong, J … - Cell Research, 2007 - nature.com The capacity for self-renewal and differentiation of human embryonic stem (ES)
cells makes them a potential source for generation of pancreatic beta cells for
treating type I diabetes mellitus. Here, we report a newly developed and ... Cited by 44 - Related articles - BL Direct - All 7 versions
- ►ucla.edu [PDF] P Gadue, TL Huber, MC Nostro, S Kattman, … - Experimental hematology, 2005 - Elsevier Embryonic stem (ES) cells have the potential to develop into all cell types of
the adult body. This capability provides the basis for considering the ES cell
system as a novel and unlimited source of cells for replacement therapies ... Cited by 27 - Related articles - All 12 versions
A Santana, R Ensenat-Waser, MI Arribas, JA … - Journal of Cellular and Molecular Medicine, 2006 - curemosladiabetes.com Type 1 diabetes is characterized by the selective destruction of pancreatic
ß-cells caused by an autoimmune attack. Type 2 diabetes is a more complex
pathology which, in addition to ß-cell loss caused by apoptotic programs, ... Cited by 25 - Related articles - View as HTML - BL Direct - All 5 versions
IS Schroeder, A Rolletschek, P Blyszczuk, G … - Nature Protocols, 2006 - nature.com Here, we describe a basic protocol for the in vitro differentiation of mouse
embryonic stem (ES) cells into insulin-producing cells. The three-step protocol
comprises (i) the formation of embryoid bodies, (ii) the spontaneous ... Cited by 20 - Related articles - BL Direct - All 3 versions
JG Lees, SA Lim, T Croll, G Williams, S Lui, … - Regenerative Med., 2007 - Future Medicine Figure 1.3D cell culturing and transplantation procedure. ... (A) Alkaline
phosphatase staining of hESC colonies. (B)Stage-specific embryonic antigen-4
immunostaining of hESC colony. (C–D) Scanning electron microscopy (SEM) ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►alphamedpress.org N Shiraki, T Yoshida, K Araki, A Umezawa, Y … - Stem Cells, 2008 - AlphaMed Press The generation of specific lineages of the definitive endoderm from embryonic
stem (ES) cells is an important issue in developmental biology, as well as in
regenerative medicine. This study demonstrates that ES cells are induced ... Cited by 15 - Related articles - BL Direct - All 6 versions