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Scholar Results 1 - 10 of about 124 citing Jaeckel: Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. (0.13 sec) 

[PDF] Mechanisms of suppression by suppressor T cells


H von Boehmer - Nature immunology, 2005 - medmicro.wisc.edu
The finding that suppressor activity is enriched in CD4+CD25+ cells has
permitted further phenotypic and functional characterization of this elusive
subset of T cells1. Although CD4+CD25+ cells express an αβ T cell ...
Cited by 580 - Related articles - All 11 versions

Foxp3 CD25 CD4 natural regulatory T cells in dominant self-tolerance and autoimmune …


S Sakaguchi, M Ono, R Setoguchi, H Yagi, S … - Immunol. Rev, 2006 - interscience.wiley.com
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Cited by 364 - Related articles - BL Direct - All 4 versions

FOXP3 controls regulatory T cell function through cooperation with NFAT

- cell.com
Y Wu, M Borde, V Heissmeyer, M Feuerer, AD … - Cell, 2006 - Elsevier
Antigen stimulation of immune cells activates the transcription factor NFAT, a
key regulator of T cell activation and anergy. NFAT forms cooperative complexes
with the AP-1 family of transcription factors and regulates T cell ...
Cited by 288 - Related articles - All 16 versions

Defective regulatory and effector T cell functions in patients with FOXP3 mutations

- nih.gov
R Bacchetta, L Passerini, E Gambineri, M Dai, … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
1 San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy. 2
Pediatrics Department, “A. Meyer” Children's Hospital, University of
Florence, Florence, Italy. 3 Department of Surgery, University of British ...
Cited by 132 - Related articles - BL Direct - All 11 versions

Where CD4+ CD25+ T reg cells impinge on autoimmune diabetes

- rupress.org
Z Chen, AE Herman, M Matos, D Mathis, C … - Journal of Experimental Medicine, 2005 - jem.rupress.org
Foxp3 is required for the generation and activity of CD4 + CD25 + regulatory T
(T reg) cells, which are important controllers of autoimmunity, including type-1
diabetes. To determine where T reg cells affect the diabetogenic cascade, ...
Cited by 103 - Related articles - BL Direct - All 11 versions

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore …

- rupress.org
KV Tarbell, L Petit, X Zuo, P Toy, X Luo, A … - Journal of Experimental Medicine, 2007 - jem.rupress.org
Most treatments that prevent autoimmune diabetes in nonobese diabetic (NOD) mice
require intervention at early pathogenic stages, when insulitis is first
developing. We tested whether dendritic cell (DC)–expanded, islet ...
Cited by 96 - Related articles - BL Direct - All 8 versions

Depletion of CD4 CD25 human regulatory T cells in vivo: kinetics of Treg depletion and …


K Mahnke, K Schonfeld, S Fondel, S Ring, S … - Int. J. Cancer, 2007 - interscience.wiley.com
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Cited by 69 - Related articles - BL Direct - All 3 versions

Homing to suppress: address codes for Treg migration

- pasteur.ac.ir [PDF] 
J Huehn, A Hamann - Trends in immunology, 2005 - Elsevier
Compelling evidence suggests that diverse types of immune reactions can be
suppressed by CD25 + CD4 + regulatory T cells (Tregs). Although increasing
knowledge has accumulated concerning the generation and functional ...
Cited by 62 - Related articles - All 6 versions

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta

- jimmunol.org
RK Selvaraj, TL Geiger - The Journal of Immunology, 2007 - Am Assoc Immnol
TGF- induces Foxp3 expression in stimulated T cells. These Foxp3 + cells
(induced regulatory T cells (iTreg)) share functional and therapeutic properties
with thymic-derived Foxp3 + regulatory T cells (natural regulatory T cells ( ...
Cited by 49 - Related articles - All 5 versions

Regulated compartmentalization of programmed cell death-1 discriminates CD4+ CD25+ …

- jimmunol.org
G Raimondi, WJ Shufesky, D Tokita, AE … - The Journal of Immunology, 2006 - Am Assoc Immnol
More effective discrimination between CD4 + CD25 + regulatory T cells (Treg) and
activated T cells would significantly improve the current level of purification
of Treg and their therapeutic application. We observed that 90% of Treg ( ...
Cited by 47 - Related articles - BL Direct - All 4 versions


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