- ►ccf.org [PDF] AJ McCullough - Journal of Clinical Gastroenterology, 2006 - journals.lww.com Abstract: Nonalcoholic fatty liver disease (NAFLD) affects ap- proximately 30% of adults and
20% of children in the United States. Nonalcoholic steatohepatitis (NASH) is its most severe
histologic form and progresses to cirrhosis in 20% of these patients. Once developed, ... Cited by 97 - Related articles - BL Direct - All 5 versions
WS Wu - Cancer and Metastasis Reviews, 2006 - Springer Abstract Reactive oxygen species (ROS) are recently proposed to be involved in tumor metastasis
which is a complicated processes including epithelial–mesenchymal transition (EMT),
migration, invasion of the tumor cells and angiogenesis around the tumor lesion. ROS ... Cited by 82 - Related articles - BL Direct - All 5 versions
- ►nih.gov JD Lambeth - Free Radical Biology and Medicine, 2007 - Elsevier Reactive oxygen species (ROS) are considered to be chemically reactive with and damaging
to biomolecules including DNA, protein, and lipid, and excessive exposure to ROS induces oxidative
stress and causes genetic mutations. However, the recently described family of Nox and ... Cited by 81 - Related articles - All 5 versions
M Genestra - Cellular signalling, 2007 - Elsevier Oxidative stress is an increase in the reduction potential or a large decrease in the reducing
capacity of the cellular redox couples. A particularly destructive aspect of oxidative stress is the
production of reactive oxygen species (ROS), which include free radicals and peroxides. ... Cited by 66 - Related articles - All 4 versions
A Bloch-Damti, N Bashan - Antioxidants & Redox Signaling, 2005 - liebertonline.com T YPE 2 DIABETES MELLITUS (T2DM) represents the final stage of a chronic and progressive
syndrome represent- ing a heterogenous disorder caused by various combinations of insulin
resistance and decreased pancreatic ß-cell func- tions. Insulin increases glucose uptake ... Cited by 45 - Related articles - BL Direct - All 3 versions
- ►physoc.org ME Sandstrom, SJ Zhang, J Bruton, JP Silva, … - The Journal of …, 2006 - Physiological Soc Exercise increases glucose transport into skeletal muscle via a pathway that is poorly
understood. We investigated the role of endogenously produced reactive oxygen species
(ROS) in contraction-mediated glucose transport. Repeated contractions increased 2- ... Cited by 46 - Related articles - BL Direct - All 7 versions
- ►nih.gov JMA Tullet, M Hertweck, JH An, J Baker, JY Hwang, S … - Cell, 2008 - Elsevier Insulin/IGF-1-like signaling (IIS) is central to growth and metabolism and has a conserved role
in aging. In C. elegans, reductions in IIS increase stress resistance and longevity, effects that
require the IIS-inhibited FOXO protein DAF-16. The C. elegans transcription factor SKN-1 ... Cited by 35 - Related articles - All 11 versions
J Pi, Y Bai, Q Zhang, V Wong, LM Floering, K Daniel, … - Diabetes, 2007 - Am Diabetes Assoc One of the unique features of β-cells is their relatively low expression of many antioxidant
enzymes. This could render β-cells susceptible to oxidative damage but may also provide a system
that is sensitive to reactive oxygen species as signals. In isolated mouse islets and INS-1( ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►physiology.org [PDF] D Feliers, Y Gorin, G Ghosh-Choudhury, … - American Journal of …, 2005 - Am Physiological Soc Page 1. Feliers et al. F-00331-2005.R1 1 Angiotensin II stimulation of VEGF mRNA translation
requires production of reactive oxygen species Denis Feliers, Yves Gorin, Goutam
Ghosh-Choudhury, Hanna E. Abboud and Balakuntalam S. Kasinath ... Cited by 31 - Related articles - BL Direct - All 7 versions
