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Scholar Results 1 - 10 of about 25 citing Pencek: 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside causes acute hepatic insulin.... (0.08 sec) 

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of …

- nih.gov
B Viollet, M Foretz, B Guigas, S Horman, R … - The Journal of physiology, 2006 - Physiological Soc
It is now becoming evident that the liver has an important role in the control
of whole body metabolism of energy nutrients. In this review, we focus on recent
findings showing that AMP-activated protein kinase (AMPK) plays a major ...
Cited by 80 - Related articles - BL Direct - All 9 versions

5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside and Metformin Inhibit Hepatic …

- shouxi.net
B Guigas, L Bertrand, N Taleux, M Foretz, N … - Diabetes, 2006 - Am Diabetes Assoc
AMP-activated protein kinase (AMPK) controls glucose uptake and glycolysis in
muscle. Little is known about its role in liver glucose uptake, which is
controlled by glucokinase. We report here that ...
Cited by 44 - Related articles - BL Direct - All 6 versions

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and …

- nih.gov
TD King, L Song, RS Jope - Biochemical pharmacology, 2006 - Elsevier
AMP-activated protein kinase (AMPK) is a key cellular sensor of reduced energy
supply that is activated by increases in the cellular ratio of AMP/ATP.
Phenformin and 5-aminoimidazole-4-carboxamide riboside (AICAR) are two ...
Cited by 28 - Related articles - All 5 versions

5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside acutely stimulates skeletal muscle …

- diabetesjournals.org
DJ Cuthbertson, JA Babraj, KJW Mustard, MC … - Diabetes, 2007 - Am Diabetes Assoc
Activation of AMP-activated protein kinase (AMPK) in rodent muscle by exercise,
metformin, 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside (AICAR), and
adiponectin increases glucose uptake. The aim of this study was to ...
Cited by 22 - Related articles - BL Direct - All 6 versions

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative …


B Guigas, N Taleux, M Foretz, D Detaille, F … - The Biochemical journal, 2007 - pubmedcentral.nih.gov
AICA riboside (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) has been
extensively used in cells to activate the AMPK (AMP-activated protein kinase), a
metabolic sensor involved in cell energy homoeostasis. In the present ...
Cited by 20 - Related articles - BL Direct - All 7 versions

Energy state of the liver during short-term and exhaustive exercise in C57BL/6J mice

- physiology.org
RC Camacho, EP Donahue, FD James, ED … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
A portal venous 5-aminoimidazole-4-carboxamide-1- -D-ribofuranoside infusion
that results in hepatic 5-aminoimidazole-4-carboxamide-1- -D-ribosyl-5-
monophosphate (ZMP) concentrations of 4 µmol/g liver increases hepatic ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Portal venous 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside infusion overcomes …

- diabetesjournals.org
RC Camacho, RR Pencek, DB Lacy, FD … - Diabetes, 2005 - Am Diabetes Assoc
AMP-activated protein kinase (AMPK) plays a key role in regulating metabolism,
serving as a metabolic master switch. The aim of this study was to assess
whether increased concentrations of the AMP analog, 5-aminoimidazole-4- ...
Cited by 13 - Related articles - All 5 versions

[PDF] Thermogenic and metabolic antiobesity drugs: rationale and opportunities


JC Clapham, JR Arch - Diabetes Obes Metab, 2007 - ephedraguide.com
Antiobesity drugs that target peripheral metabolism may avoid some of the
problems that have been encountered with centrally acting anorectic drugs.
Moreover, if they cause weight loss by increasing fat oxidation, they not ...
Cited by 9 - Related articles - View as HTML - All 4 versions

AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 …

- jbc.org
Y Zang, LF Yu, T Pang, LP Fang, X Feng, TQ … - Journal of Biological Chemistry, 2008 - ASBMB
Neural stem cell differentiation and the determination of lineage decision
between neuronal and glial fates have important implications in the study of
developmental, pathological, and regenerative processes. Although small ...
Cited by 9 - Related articles - All 3 versions

AICAR positively regulate glycogen synthase activity and LDL receptor expression …


HM Wang, S Mehta, R Bansode, W Huang, … - Biochemical Pharmacology, 2008 - Elsevier
5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) is a commonly used
pharmacological agent to study physiological effects which are similar to those
of exercise. However, signal transduction pathways by which AICAR elicits ...
Cited by 7 - Related articles - All 2 versions


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