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Scholar Results 1 - 10 of about 29 citing Modesti: Hyperglycemia Activates JAK2 Signaling Pathway in Human Failing Myocytes via Angiotensin.... (0.08 sec) 

Hyperglycemia is a marker for poor outcome in the postoperative pediatric cardiac …

- critcaremed.com
AR Yates, PC Dyke, R Taeed, TM Hoffman, J Hayes, TF … - diabetes - pdfs.journals.lww.com
In pediatric populations, it has been known that hyperglycemia is associated with poor outcomes
for patients receiving skin grafts for thermal injury, for patients with neurologic trauma, and for
neonates with necrotizing enterocolitis (9 –12). Re- cently, two studies have ...
Cited by 46 - Related articles - All 7 versions

Increased expression of NAD (P) H oxidase in islets of animal models of Type 2 …


M Nakayama, T Inoguchi, T Sonta, Y Maeda, S … - … and Biophysical Research …, 2005 - Elsevier
This study was undertaken to reveal the role of NAD(P)H oxidase in increased oxidative stress
in islets of Type 2 diabetes. Immunostaining analysis showed that staining intensities of
NAD(P)H oxidase components, gp91phox and p22phox, significantly increased in islets ...
Cited by 42 - Related articles - All 6 versions

NADPH oxidase and heart failure


CE Murdoch, DJ Grieve, AC Cave, YH Looi, AM … - Current Opinion in …, 2006 - Elsevier
Reactive oxygen species play important roles in the pathophysiology of chronic heart failure
secondary to chronic left ventricular hypertrophy or myocardial infarction. Reactive oxygen species
influence several components of the phenotype of the failing heart, including contractile ...
Cited by 25 - Related articles - All 2 versions

Energy deficiency in the failing heart: linking increased reactive oxygen species …


FL Sheeran, S Pepe - BBA-Bioenergetics, 2006 - Elsevier
Heart failure is a complex syndrome of numerous dysfunctional components which converge
to cause chronic progressive failure of ventricular contractile function and maintenance of cardiac
output demand. The aim of this brief review is to highlight some of the mounting evidence ...
Cited by 18 - Related articles - All 4 versions

Long-term effects of increased glucose entry on mouse hearts during normal aging …

- ahajournals.org
I Luptak, J Yan, L Cui, M Jain, R Liao, R Tian - Circulation, 2007 - Am Heart Assoc
Methods and Results— We performed a 2-year follow-up study in transgenic mice with sustained
high glucose uptake and utilization in the heart by cardiac-specific overexpression of the
insulin-independent glucose transporter GLUT1 (GLUT1-TG). Compared with wild-type ...
Cited by 12 - Related articles - All 4 versions

Renal mitochondrial impairment is attenuated by AT1 blockade in experimental …

- physiology.org
E de Cavanagh, L Ferder, JE Toblli, B … - American Journal of …, 2008 - Am Physiological Soc
To investigate whether ANG II type 1 (AT 1 ) receptor blockade could protect kidney mitochondria
in streptozotocin-induced Type 1 diabetes, we treated 8-wk-old male Sprague-Dawley rats with
a single streptozotocin injection (65 mg/kg ip; STZ group), streptozotocin and drinking ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Angiotensin II and the cardiac complications of diabetes mellitus


KA Connelly, AJ Boyle, DJ Kelly - Current pharmaceutical design, 2007 - ingentaconnect.com
Abstract: The prevalence of diabetes has reached epidemic proportions in the developed world
and is expect to increase to 5.4% by 2025. This has resulted in an unprecedented number of
patients experiencing the macro- and micro-vascular complications of diabetes, such as ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic …


R Li, N Yang, L Zhang, Y Huang, R Zhang, F Wang, … - Am J Nephrol, 2007 - content.karger.com
Background/Aims: This study investigated the role of JAK/STAT, an important pathway for cytokine
signal transduction, in the progression of chronic glomerular diseases. Methods: BALB/c mice
received a single intravenous injection of adriamycin (10 mg/kg) were sacrificed 2, 4 and ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human …

- nutrition.org
JS Choi, YJ Choi, SY Shin, J Li, SW Kang, JY Bae, … - Journal of …, 2008 - Am Soc Nutrition
Endothelial apoptosis is a driving force in atherosclerosis development. Oxidized LDL promotes
inflammatory and thrombotic processes and is highly atherogenic, as it stimulates macrophage
cholesterol accumulation and foam cell formation. This study investigated multiple ...
Cited by 4 - Related articles - All 5 versions

Reduced expression of thyroid hormone receptors and beta-adrenergic receptors …


PA Modesti, M Marchetta, T Gamberi, G Lucchese, … - Biochemical …, 2008 - Elsevier
An altered thyroid hormone profile has been reported in patients with congestive heart
failure. However, information regarding the status of thyroid hormone receptors in human failing
cardiomyocytes is lacking. Therefore the expression of thyroid hormone and ...
Cited by 2 - Related articles - All 2 versions


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