M Araki, SM Flechner, HR Ismail, LM Flechner … - Transplantation, 2006 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JA Emamaullee, AM Shapiro - Diabetes, 2006 - Am Diabetes Assoc A substantial proportion of the transplanted islet mass fails to engraft due to
death by apoptosis, and a number of strategies have been explored to inhibit
β-cell loss. Inhibition of extrinsic signals of apoptosis (ie, cFLIP or ... Cited by 31 - Related articles - BL Direct - All 10 versions
CT Bussiere, JRT Lakey, AMJ Shapiro, GS … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis The Edmonton Protocol for islet trans- plantation has
provided hope for type 1 diabetic patients. However, this protocol requires
lifelong immunosuppres- sion, specifically sirolimus, a cellular ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►shouxi.net JA Emamaullee, RV Rajotte, P Liston, RG … - Diabetes, 2005 - Am Diabetes Assoc The Edmonton Protocol for treatment of type 1 diabetes requires islets from two
or more donors to achieve euglycemia in a single recipient, primarily because
soon after portal infusion, the majority of the transplanted cells undergo ... Cited by 24 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org JA Emamaullee, L Stanton, C Schur, AM … - Diabetes, 2007 - Am Diabetes Assoc Islet transplantation can provide insulin independence in patients with type 1
diabetes, but islets derived from two or more donors are often required. A
significant fraction of the functional islet mass is lost to apoptosis in ... Cited by 21 - Related articles - BL Direct - All 5 versions
- ►shouxi.net A Plesner, P Liston, R Tan, RG Korneluk, CB … - Diabetes, 2005 - Am Diabetes Assoc Allotransplantation of pancreatic islets represents a promising approach to
treat type 1 diabetes. Destruction of β-cells in islet allografts involves
multiple immune mechanisms that lead to activation of caspases and ... Cited by 14 - Related articles - BL Direct - All 6 versions
SE Cross, SK Richards, A Clark, AV Benest, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Vascular endothelial growth factor as a survival factor for
human islets: effect of immunosuppressive drugs SE Cross ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►daegu.ac.kr [PDF] S Marcelli-Tourvieille, T Hubert, E Moerman … - Transplantation, 2007 - journals.lww.com Skip Navigation Links Home > March 15, 2007 - Volume 83 - Issue 5 > In Vivo and
In Vitro Effect of Sirolimus on Insulin Secretio... ... 1 Department of
Endocrinology and Metabolism and Endocrine Surgery, INSERM Unit-M859, ... Cited by 10 - Related articles - BL Direct - All 6 versions
- ►endojournals.org OT Hardy, HE Hohmeier, TC Becker, E … - Molecular Endocrinology, 2007 - Endocrine Soc Recent advances in functional genomics afford the opportunity to interrogate the
expression profiles of thousands of genes simultaneously and examine the
function of these genes in a high-throughput manner. In this study, we ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org MD McKenzie, EM Carrington, T Kaufmann, A … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Development and function of islets were not affected by loss of Bid,
and Bid-deficient islets were as susceptible as wild-type islets to cytotoxic
stimuli that cause apoptosis via the mitochondrial pathway. In contrast, ... Cited by 11 - Related articles - BL Direct - All 3 versions
