- ►diabetesjournals.org CJ Nolan, MSR Madiraju, V Delghingaro-Augusto, ML … - Diabetes, 2006 - Am Diabetes Assoc Fatty acids (FAs) and other lipid molecules are important for many cellular functions, including
vesicle exocytosis. For the pancreatic β-cell, while the presence of some FAs is essential for
glucose-stimulated insulin secretion, FAs have enormous capacity to amplify glucose- ... Cited by 55 - Related articles - BL Direct - All 5 versions
SM Ronnebaum, O Ilkayeva, SC Burgess, JW … - Journal of Biological …, 2006 - ASBMB Glucose-stimulated insulin secretion (GSIS) from pancreatic islet β-cells is central to control of
mammalian fuel homeostasis. Glucose metabolism mediates GSIS in part via ATP-regulated
K + (K ATP ) channels, but multiple lines of evidence suggest participation of other ... Cited by 42 - Related articles - All 5 versions
RW Brownsey, AN Boone, JE Elliott, JE … - Biochemical Society …, 2006 - biochemsoctrans.cn Abstract Acetyl-CoA carboxylase (ACC) catalyses the formation of malonyl-CoA, an essential
substrate for fatty acid synthesis in lipogenic tissues and a key regulatory molecule in
muscle, brain and other tissues. ACC contri- butes importantly to the overall control of ... Cited by 39 - Related articles - View as HTML - BL Direct - All 6 versions
- ►nih.gov MV Chakravarthy, Y Zhu, M López, L Yin, … - Journal of Clinical …, 2007 - Am Soc Clin Investig 1 Department of Internal Medicine, Division of Endocrinology, Metabolism and Lipid
Research, Washington University School of Medicine, St. Louis, Missouri, USA. 2 Department
of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Cambridge, ... Cited by 33 - Related articles - BL Direct - All 8 versions
- ►unige.ch [PDF] P Maechler, S Carobbio, B Rubi - International Journal of Biochemistry and Cell …, 2006 - Elsevier Pancreatic beta-cells are unique neuroendocrine cells displaying the peculiar feature of responding
to nutrients, principally glucose, as primary stimulus. This requires translation of a metabolic
substrate into intracellular messengers recognized by the exocytotic machinery. Central ... Cited by 29 - Related articles - All 7 versions
C Guay, SR Madiraju, A Aumais, E Joly, M Prentki - Journal of Biological …, 2007 - ASBMB In pancreatic β-cells, metabolic coupling factors generated during glucose metabolism and pyruvate
cycling through anaplerosis/cataplerosis processes contribute to the regulation of insulin
secretion. Pyruvate/citrate cycling across the mitochondrial membrane leads to the ... Cited by 25 - Related articles - All 4 versions
… , SL Macaulay, MA Febbraio, BE Kemp - Canadian journal of …, 2006 - article.pubs.nrc-cnrc.gc.ca Abstract: AMP-activated protein kinase plays an important role in the regulation of lipid metabolism
in response to meta- bolic stress and energy demand. It is also under endocrine control. AMPK
acts at multiple steps and has a central role controlling fatty acid, triglyceride, and ... Cited by 18 - Related articles - BL Direct - All 6 versions
- ►physiology.org D Sebastian, L Herrero, D Serra, G Asins, … - American Journal of …, 2007 - Am Physiological Soc Oversupply of lipids to skeletal muscle causes insulin resistance by promoting the accumulation
of lipid-derived metabolites that inhibit insulin signaling. In this study, we tested the hypothesis
that overexpression of carnitine palmitoyltransferase I (CPT I) could protect myotubes ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►psu.edu [PDF] AR Ortiz, P Gomez-Puertas, A Leo-Macias, … - Current Topics in …, 2006 - ingentaconnect.com 1 Bioinformatics Unit, Centro de Biologia Molecular “Severo Ochoa” (CSIC-UAM)
Cantoblanco, 28049 Madrid (Spain); 2 Department of Physiology and Biophysics, Weill Medical
College of Cornell University, 1300 York Avenue, New York, NY 10021 (USA); 3 The ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►jbc.org AY Sierra, E Gratacos, P Carrasco, J Clotet, J … - Journal of Biological …, 2008 - ASBMB CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the
brain. The enzyme has recently been localized in neuron mitochondria. Although it has high
sequence identity with the other two CPT1 isoenzymes (a and b), no CPT activity has ... Cited by 14 - Related articles - All 3 versions
